A Case of Desmoplastic Trichilemmoma of the Lip Treated with Mohs Surgery

Schweiger, Eric S; Spann, Candace Thornton; Weinberg, Jeffrey M; Ross, Bonnie

doi:10.1111/j.1524-4725.2004.30318.x

Cited by 15 publications

(19 citation statements)

References 13 publications

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“…In what concerns DT treatment, although usually benign, its potential coexistence with atypical basaloid cell proliferations including CBC, makes Mohs surgery (for both adequate margin control and tissue sparing benefits) 15,21 or complete surgical excision with pathological confirmation of clear margins the treatments of choice. 22 In summary, a case of a patient with a desmoplastic trichilemmoma arising in a nevus sebaceous of the scalp is reported.…”

Section: Discussionmentioning

confidence: 99%

Triquilemoma Desmoplástico em Nevo Sebáceo do Couro Cabeludo

Tavares‐Bello

Fernandes

2016

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RESUMO -Descrito originalmente por Jadassohn em 1895, foi apenas em 1932 que a designação "nevo sebáceo" foi introduzida, por Robinson. Trata-se de um hamartoma congénito relativamente prevalente que, classicamente, evolui por fases de crescimento e maturação (classicamente estão descritas 3 fases: infância <12; adolescência 12-18; adultos >18) e que, do 4º ao 7º decénios pode originar, em 10-30% dos casos), várias neoplasias epiteliais. Muito raramente reportados neste contexto, os triquilemomas são tumores anexiais benignos que se originam ou diferenciam no epitélio da bainha radicular externa folicular. Habitualmente solitários, podem apresentar-se clinicamente como pápulas translúcidas ou queratósicas faciais, em particular na proximidade da pirâmide nasal e dos lábios. A rara variante histológica "triquilemoma desmoplásico" pode simular clinicamente basaliomas (CBC), carcinomas espinhocelulares (CEC), nevos intradérmicos, verrugas virais, cornos cutâneos ou hiperplasias sebáceas e, histologicamente, evocar variantes desmoplásicas de CBCs, CECs e de carcinomas triquilémicos. É apresentado caso de doente eurocaucasiano de 56 anos de idade que apresentava pápulas e nódulos translúcidos assintomáticos, desenvolvidos num nevo sebáceo do couro cabeludo. O estudo histológico revelou uma proliferação lobular com as características clássicas do triquilemoma desmoplásico no seio de um hamartoma sebáceo. O caso é ilustrado iconograficamente e a literatura relevante é sumariamente revista. PALAVRAS-CHAVE -Nevo; Neoplasias das Glândulas Sebáceas; Neoplasias da Pele. Desmoplastic Trichilemmoma arising on a Nevus Sebaceous of the Scalp ABSTRACT -Originally described by Jadassohn in 1895, it was not until 1932 that the term "nevus sebaceous" was introduced by Robinson. It is a prevalent benign congenital hamartoma that classically evolves through discrete phases of growth and that

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Section: Discussionmentioning

confidence: 99%

Triquilemoma Desmoplástico em Nevo Sebáceo do Couro Cabeludo

Tavares‐Bello

Fernandes

2016

SPDV

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“…In 1990, Hunt and colleagues described a clinical variant of the neoplasm, the desmoplastic trichilemmoma, characterized by a central zone of desmoplasia, which can clinically simulate an invasive carcinoma. 1,2,3 …”

Section: Discussionmentioning

confidence: 99%

“…1,4 A tumor suppressor gene named PTEN/MMAC1 has been reported as the causal agent. 5 Some authors consider it to be a kind of viral wart based on the findings of conventional microscopic sections.…”

Section: Discussionmentioning

confidence: 99%

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A rare clinical presentation of Desmoplastic Trichilemmoma mimicking Invasive Carcinoma

Sano¹,

Yang²,

Tebcherani³

et al. 2014

An. Bras. Dermatol.

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“…In the latest WHO International Histological Classification of Tumors of Domestic Animal, tricholemmoma is classified into inferior and isthmic variants, depending on differentiation to the distinct two outer root sheath compartments [6]. In human, several reports on desmoplastic tricholemmoma had been published [3, 7, 12, 13], but this variant has never been reported in the canine counterpart. The present study describes histopathological and immunohistochemical findings of desmoplastic tricholemmoma in a dog.…”

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confidence: 99%

Desmoplastic tricholemmoma in a dog

Kok

Chambers

Dohata

et al. 2017

The Journal of Veterinary Medical Science

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A 10-year-old mixed breed dog was presented with a 0.8 cm diameter mass below the left eye region. The mass was surgically removed and processed for histopathological examination. Microscopically, tumor cells proliferated in small lobules, nests and cords, and the tumor parenchyma was separated by desmoplastic stroma. Majority of the tumor cells were periodic acid-Schiff (PAS)-positive, and the desmoplastic stroma was densely collagenous and mucinous. Immunohistochemical results showed that the tumor cells were diffusely positive for cytokeratin 15, cytokeratin 19 and CD 34, while cytokeratin 8 reactivity was limited to the tumor cells proliferating in cords. Few tumor cells were positive for nestin. Based on the histopathological findings, the tumor was diagnosed as desmoplastic tricholemmoma.

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A Case of Desmoplastic Trichilemmoma of the Lip Treated with Mohs Surgery

Cited by 15 publications

References 13 publications

Triquilemoma Desmoplástico em Nevo Sebáceo do Couro Cabeludo

Triquilemoma Desmoplástico em Nevo Sebáceo do Couro Cabeludo

A rare clinical presentation of Desmoplastic Trichilemmoma mimicking Invasive Carcinoma

Desmoplastic tricholemmoma in a dog

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