A Case of Disseminated Carcinomatosis of Bone Marrow Due to Recurrence of Signet Ring Cell Carcinoma in Juvenile Colon Cancer

Ohnishi, Koji; Ueda, Nobuhiko; Senda, Katsunori; Nakagawara, Hisatoshi; Yoshimitsu, Yutaka; Sawa, Toshiharu

doi:10.3919/jjsa.68.136

Cited by 8 publications

(1 citation statement)

References 6 publications

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“…On the other hand, colorectal cancer is relatively rare as an origin of DCBM, with only 27 cases having been reported between 1984 and 2013 in Japan (table 2 ) [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 ]. The average patient age in these cases is 55 years, and the disease is as common in males as it is in females.…”

Section: Discussionmentioning

confidence: 99%

A Report of Disseminated Carcinomatosis of the Bone Marrow Originating from Transverse Colon Cancer Successfully Treated with Chemotherapy Using XELOX plus Bevacizumab

Naito¹,

Yoshida²,

Aisu³

et al. 2014

Case Rep Oncol

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A 61-year-old male, who had been admitted to another hospital due to disseminated intravascular coagulation (DIC), was referred to our hospital. Total colonoscopy, abdominal dynamic CT and positron-emission tomography revealed bone metastasis and multiple lymphocytic metastases from transverse colon cancer in addition to disseminated carcinomatosis of the bone marrow (DCBM). We immediately performed chemotherapy with XELOX + bevacizumab and denosumab against DCBM from transverse colon cancer in order to avoid radical surgery. In addition, we initiated the administration of recombinant human soluble thrombomodulin for 1 week to treat DIC. The patient was able to tolerate and receive 4 cycles of chemotherapy without any severe side effects. After receiving the 4 cycles of treatment, he recovered from DIC, and the bone and multiple lymphocytic metastases disappeared.

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