A Case of Disseminated Histoplasmosis

Disseminated Histoplasmosis Following Long-term Steroid Therapy for Reticulosarcoma

“…H. capsulatum was cultured from necropsy samples of lung and spleen (Dr. R. W. Riddell). was reported in a cotton-worker who handled imported materials (Miller et al, 1961), but in three cases of fatal histoplasmosis in Britain the patients had lived in India for part of their lives (Earle, Highman, and Lockey, 1960). The apparent remission in the reticulosarcomatous process suggests a good response to steroid treatment, but it is likely that this drug was the major factor in permitting the establishment of a systemic mycosis.…”

Disseminated histoplasmosis and its treatment

“…Only five cases of this type have been reported in Britain, (Derry, Card, Wilson, and Duncan, 1942;Lockey, Atkinson, Grieve, and Bridson, 1953;Poles and Lavertine, 1954;Earle, Highman, and Lockey, 1960;Miller, Ramsden and Geake, 1961). Histoplasmosis, first described by Darling in 1906, is common in N. America and Asia.…”

Attempted Suicide with Sulthiame

“…Medical Memoranda was reported in a cotton-worker who handled imported materials (Miller et al, 1961), but in three cases of fatal histoplasmosis in Britain the patients had lived in India for part of their lives (Earle, Highman, and Lockey, 1960). The apparent remission in the reticulosarcomatous process suggests a good response to steroid treatment, but it is likely that this drug was the major factor in permitting the establishment of a systemic mycosis.…”