A case of disseminated strongyloidiasis after multiple courses of immunosuppression

Abstract

Strongyloides affects up to 40% of foreign-born Canadians and is often asymptomatic.• Risk factors for hyperinfection, which is associated with a high risk of death, include use of immunosuppressant drugs (particularly corticosteroids), human T-cell leukemia virus type 1 infection and hematologic cancers.

Disseminated strongyloidiasis in a patient with rheumatoid arthritis: A case report

“…Most infected individuals are asymptomatic or present with intermittent symptoms[ 4 ]. Immunosuppressed patients can develop hyperinfection syndrome and disseminated nematode disease which have high mortality rates[ 5 - 7 ]. Strongyloidiasis has been reported following concomitant tocilizumab and methylprednisolone treatment[ 8 ].…”