A case of endometrial stromal sarcoma with curvilinear calcification

Pekindil, Gökhan; Tunçyürek, Özüm; Örgüç, Şebnem; İnceboz, Ümit; Kandiloğlu, Ali Rıza; Çağlar, Hüsnü

doi:10.1016/j.ygyno.2005.04.021

Cited by 7 publications

(12 citation statements)

References 9 publications

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“…Several studies have described the sonographic appearance of uterine sarcomas (Table S2), all of which were small and used few ultrasound variables to describe the ultrasound images, and leiomyosarcomas, endometrial stromal sarcomas and undifferentiated stromal sarcomas were usually not described separately. Exacoustos et al ,.…”

Section: Discussionmentioning

confidence: 99%

“…Bonneau et al . described ultrasound signs of calcifications in 4/20 (20.0%) benign leiomyomas and in 1/6 (16.7%) sarcomas, and Pekindil et al . described one case of endometrial stromal sarcoma with ultrasound signs of calcifications verified histologically.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have described the sonographic appearance of uterine sarcomas (Table S2) [48][49][50][51][52][53][54][55][56][57][58][59][60][61][62] , all of which were small and used few ultrasound variables to describe the ultrasound images, and leiomyosarcomas, endometrial stromal sarcomas and undifferentiated stromal sarcomas were usually not described separately. Exacoustos et al 48 , in the largest published series of leiomyosarcomas (n = 8), found that they are usually large (largest diameter > 8 cm in seven of eight cases), manifest inhomogeneous echogenicity of the solid tissue and often (in 50% of cases) contain cystic areas.…”

Section: Discussionmentioning

confidence: 99%

“…Calcifications were found in about 10% of the sarcomas in our series. Bonneau et al 62 described ultrasound signs of calcifications in 4/20 (20.0%) benign leiomyomas and in 1/6 (16.7%) sarcomas, and Pekindil et al 58 described one case of endometrial stromal sarcoma with ultrasound signs of calcifications verified histologically. Results regarding calcifications in uterine leiomyosarcomas visible on magnetic resonance imaging are conflicting 65,66 .…”

Section: Discussionmentioning

confidence: 99%

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Imaging in gynecological disease (15): clinical and ultrasound characteristics of uterine sarcoma

Ludovisi

Moro

Pasciuto

et al. 2019

Ultrasound in Obstet & Gyne

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Objective To describe the clinical and ultrasound characteristics of uterine sarcomas. Methods This was a retrospective multicenter study. From the databases of 13 ultrasound centers, we identified patients with a histological diagnosis of uterine sarcoma with available ultrasound reports and ultrasound images who had undergone preoperative ultrasound examination between 1996 and 2016. As the first step, each author collected information from the original ultrasound reports from his/her own center on predefined ultrasound features of the tumors and by reviewing the ultrasound images to identify information on variables not described in the original report. As the second step, 16 ultrasound examiners reviewed the images electronically in a consensus meeting and described them using predetermined terminology. Results We identified 116 patients with leiomyosarcoma, 48 with endometrial stromal sarcoma and 31 with undifferentiated endometrial sarcoma. Median age of the patients was 56 years (range, 26–86 years). Most patients were symptomatic at diagnosis (164/183 (89.6%)), the most frequent presenting symptom being abnormal vaginal bleeding (91/183 (49.7%)). Patients with endometrial stromal sarcoma were younger than those with leiomyosarcoma and undifferentiated endometrial sarcoma (median age, 46 years vs 57 and 60 years, respectively). According to the assessment by the original ultrasound examiners, the median diameter of the largest tumor was 91 mm (range, 7–321 mm). Visible normal myometrium was reported in 149/195 (76.4%) cases, and 80.0% (156/195) of lesions were solitary. Most sarcomas (155/195 (79.5%)) were solid masses (> 80% solid tissue), and most manifested inhomogeneous echogenicity of the solid tissue (151/195 (77.4%)); one sarcoma was multilocular without solid components. Cystic areas were described in 87/195 (44.6%) tumors and most cyst cavities had irregular walls (67/87 (77.0%)). Internal shadowing was observed in 42/192 (21.9%) sarcomas and fan‐shaped shadowing in 4/192 (2.1%). Moderate or rich vascularization was found on color‐Doppler examination in 127/187 (67.9%) cases. In 153/195 (78.5%) sarcomas, the original ultrasound examiner suspected malignancy. Though there were some differences, the results of the first and second steps of the analysis were broadly similar. Conclusions Uterine sarcomas typically appear as solid masses with inhomogeneous echogenicity, sometimes with irregular cystic areas but only very occasionally with fan‐shaped shadowing. Most are moderately or very well vascularized. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Imaging in gynecological disease (15): clinical and ultrasound characteristics of uterine sarcoma

Ludovisi

Moro

Pasciuto

et al. 2019

Ultrasound in Obstet & Gyne

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“…An association with prolonged oestrogenic stimulation, tamoxifen treatment or previous pelvic irradiation has been observed in some patients 14. Patients commonly present with abnormal vaginal bleeding and pelvic or abdominal pain; however, up to 25% of women are asymptomatic 1 3 12 14. Vaginal bleeding was the chief complaint of our patient and it was repeated a few months postcurettage.…”

Section: Discussionmentioning

confidence: 57%

Endometrial stromal sarcoma of uterus with metastasis to the lung and brain

et al. 2012

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Ultrasound features of highly vascularized uterine myomas (uterine smooth muscle tumors) and correlation with histopathology

Russo

Camilli

Martire

et al. 2022

Ultrasound in Obstet & Gyne

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What are the novel findings of this work?In our series of uterine myomas with high vascularization on ultrasound, the histological diagnosis was benign in 93% of cases, which included leiomyoma variant in 45% and adenomyoma in 6%. A malignant lesion was diagnosed in 7% of cases, all of which occurred in patients over 40 years of age. What are the clinical implications of this work?Our findings are useful in the clinical management of patients with a highly vascularized myoma identified during ultrasound assessment. Patients under 40 years of age can be managed conservatively (expectant or minimally invasive surgical management), whereas those over 40 years with a lesion that has irregular borders and without visible endometrium are at higher risk of malignancy and should preferably be managed by surgical oncologists.

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A case of endometrial stromal sarcoma with curvilinear calcification

Cited by 7 publications

References 9 publications

Imaging in gynecological disease (15): clinical and ultrasound characteristics of uterine sarcoma

Imaging in gynecological disease (15): clinical and ultrasound characteristics of uterine sarcoma

Endometrial stromal sarcoma of uterus with metastasis to the lung and brain

Ultrasound features of highly vascularized uterine myomas (uterine smooth muscle tumors) and correlation with histopathology

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