A Case of Eruptive Vellus Hair Cysts That Developed on the Labium Major

Park, Juhyuk; Her, Young; Chun, Bo Mi; Kim, Chul Woo; Kim, Sang Seok

doi:10.5021/ad.2009.21.3.294

Cited by 12 publications

(9 citation statements)

References 12 publications

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“…Facial lesions occur [4]; they were the unique localization in ten cases [2] and were unilateral in one of them [5]. Unusual sites include the back, labium major [6], the buttocks and groin [7]. The lesions are usually flesh-colored, but may be brown, red, white, bluish-grey (especially in Asian people) or yellowish [2,6] and may have an umbilicated or crusted surface [2].…”

Section: Discussionmentioning

confidence: 99%

“…Unusual sites include the back, labium major [6], the buttocks and groin [7]. The lesions are usually flesh-colored, but may be brown, red, white, bluish-grey (especially in Asian people) or yellowish [2,6] and may have an umbilicated or crusted surface [2]. Umbilication probably reflects opening of the cysts to the epidermis [8], whereby extrusion of the cyst contents may occur, possibly leading to spontaneous resolution [2].…”

Section: Discussionmentioning

confidence: 99%

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Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

Zaharia

Kanitakis²

2012

Dermatology

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Eruptive vellus hair cysts (EVHC) are rather uncommon lesions, of which 222 cases have been published in the literature. Their etiopathogenesis is poorly known. We report herein a new typical case of EVHC that was studied immunohistochemically. A 15-year-old male presented with a 4-year history of progressively developing small brown-gray papules on the trunk and extremities. Microscopically the lesions consisted of small epidermoid cysts containing vellus hairs. Immunohistochemically, the lesions expressed keratin 1/10, calretinin and p63 but no epithelial membrane antigen, filaggrin or androgen receptors. A review of the relevant literature shows that EVHC may be inherited or acquired and may be associated to other genodermatoses, namely sebocystomatosis. They could be due to hamartomatous follicular growth, to a trouble in infundibular keratinization leading to vellus hair follicle occlusion, or represent an example of acquired hamartoma. Although benign, this condition is difficult to treat.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

Zaharia

Kanitakis²

2012

Dermatology

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“…Six patients were Asian, two were White, and one was of unknown race. In five cases the lesions were morphologically [78] with permission].…”

Section: Unilesional Evhcmentioning

confidence: 99%

Eruptive Vellus Hair Cysts

Torchia

Vega

Schachner

2012

American Journal of Clinical Dermatology

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“…EVHC may develop on almost any body site but vulval involvement has been found in only two previous cases. 1,4 One of our patients presented with vulval lesions.…”

Section: Reportmentioning

confidence: 98%

Clinicopathological features and expression of four keratins (K10, K14, K17 and K19) in six cases of eruptive vellus hair cysts

et al. 2014

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Six cases of eruptive vellus hair cysts (EVHC) were evaluated for histopathology and the immunohistochemical profile of Ki-67 and four keratins (K10, K14, K17 and K19). The pathological hallmark of EVHC was the existence of vellus hair shafts within the cystic cavity, but atypical pathological changes included two or three cysts and a foreign-body granuloma in three cases. Our results demonstrate that atypical pathological changes are not uncommon in EVHC, and indicate that based on keratin expression, it is likely that EVHC is derived from the infrainfundibulum and sebaceous duct.

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A Case of Eruptive Vellus Hair Cysts That Developed on the Labium Major

Cited by 12 publications

References 12 publications

Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

Eruptive Vellus Hair Cysts

Clinicopathological features and expression of four keratins (K10, K14, K17 and K19) in six cases of eruptive vellus hair cysts

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