A case of Evans syndrome associated with autoimmune thyroiditis

Abstract

Introduction: Evans syndrome is the occurrence of immune-mediated thrombocytopenia in the conjunction with autoimmune hemolytic anemia (AIHA). On the other hand, autoimmune thyroiditis is the presence of antibodies directed to thyroid peroxidase, thyroglobulin and thyroid stimulating hormone receptor. The association of Evans syndrome with hypothyroidism or autoimmune thyroiditis is extremely rare. Case: We present an 8-year-old boy as the first such case in pediatric population diagnosed with Evans syndrome and neutropenia associated with autoimmune hypothyroidism. Conclusion: As autoimmune diseases can occur simultaneously, we emphasize the need to perform appropriate investigations in patients with autoimmune cytopenias.

Evans Syndrome and Hashimoto's Thyroiditis in Pregnancy: A Case Report

“…Globally, the incidence of Evans syndrome accompanied by Hashimoto's thyroiditis is only 2%, so clinically, this case is very rare (Oh et al 2011). There is no theory that can link Evans syndrome and Hashimoto's thyroiditis; one hypothesis is the possibility that these two diseases have the same immunopathogenic pathway that causes a person affected by one of these autoimmune conditions to be susceptible to other autoimmune diseases that are associated with the first autoimmune conditions such as Evans syndrome and Hashimoto's thyroiditis (Hanafy et al 2018). Associated with pregnancy itself can affect the condition of Evans syndrome and Hashimoto's thyroiditis disorder experienced by the patient.…”