A Case of Fatal Bleeding Following Emergency Surgery on an Ascending Aorta Intramural Hematoma in a Patient Taking Dabigatran

2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery

“…Because emergency surgery in patients under dabigatran treatment has been associated with severe or even fatal bleeding, it is recommended that DOACs be discontinued at least 48 h before cardiac surgery. [78][79][80] DOACs may be bridged by heparins in patients with acute thrombotic events o 4 weeks. The half-life of DOACs may be prolonged in case of impaired renal function (Table 3).…”

Idarucizumab for Dabigatran Reversal in Emergency Type-A Aortic Dissection

“…Yeoh et al reported lung injury from the use of a suction catheter via the DLT and stated that the suction tip penetrated into the normal lung tissue. 1 To the best of our knowledge, our report is the first case of pulmonary hemorrhage resulting from suction catheter placement during VATS. Lung collapse is important for adequate surgical exposure during VATS.…”

“…5 The median age of these patients was 76 years old, similar to our patient and others (76 to 82 years old). [1][2][3] Hemostasis during the procedure was clinically judged to be adequate in 92% of cases, but with a high mortality rate of 23.1%, mainly due to cardiovascular causes.…”

“…Furthermore, we agree with the recommendation of Yeoh and colleagues to avoid unintended and preventable complications from endobronchial suction catheters. 1…”

Point-of-Care Coagulation Tests Monitoring of Direct Oral Anticoagulants and Their Reversal Therapy: State of the Art

“…Following platelets and fibrinogen concentrate administration, clot strength recovered, but time to clot formation was still prolonged and even the subsequent administration of rFVIIa failed to normalize CT at EXTEM. 51…”