A Case of Female Acute Urinary Retention Presenting to the ED

Swartzberg, Kylen; Adam, Ahmed; Motara, Feroza; Laher, Abdullah E.

doi:10.1155/2017/4598314

Cited by 6 publications

(8 citation statements)

References 13 publications

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“…Also, neurological impairment can cause or exacerbate urinary retention by interrupting the sensory and/or motor innervation of the detrusor muscle 4 . Furthermore, diabetes mellitus can also contribute to AUR due to neuropathy developed from myogenic and neurogenic alterations as a result of prolonged hyperglycemia and production of oxidative stress products 10–13 . In our study, we also similarly found that the rates of AUR occurrence were higher in patients with diabetes and neurological diseases.…”

Section: Discussionsupporting

confidence: 82%

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Characteristics of recurrent acute urinary retention in BPH patients in the United States: Retrospective analysis of US‐based insurance claims database

et al. 2023

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Purpose: The objective of this study is to analyze characteristics of recurrent acute urinary retention (AUR) in patients with benign prostatic hyperplasia (BPH), utilizing a population based data set. Also, we sought to report on how AUR was treated, specifically regarding the need and length of catheterization and types of procedures utilized for mitigation. Materials & Methods: A retrospective observational cohort study was performed using Optum's deidentified Clinformatics ® Data Mart Database. We compared two groups, BPH patients with AUR (n = 180,737) and BPH patients without AUR (n = 1,139,760) from January 1, 2003 to December 31, 2017. Also, we analyzed the factors affecting the development of multiple episodes of AUR through age-adjusted multivariate analysis.Results: In contrast to the 47.7% of patients who had a single AUR episode, 33.5% of AUR patients developed 3 or more subsequent episodes of retention. For age matched patients, the risks of additional episodes of retention increase significantly with older age, Caucasian race, diabetes, neurologic conditions, or low income.Overall, the rate of BPH surgery in AUR patients over the study period decreased and the most common procedure was transurethral resection of the prostate.Conclusions: Risk factors for multiple episodes of AUR included age (60 and older), Caucasian race, lower income socioeconomic status, diabetes, and neurological disorders. Patients with a high probability of developing recurrent episodes of AUR are recommended to receive preemptive BPH medication before such AUR occurrences. Also, more expeditious surgical treatment should be considered rather than temporary catheterization when AUR occurs.

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Section: Discussionsupporting

confidence: 82%

“…The incidence of AUR in BPH patients also increases in patients with comorbid conditions such as diabetes and neurological diseases 10–13 . The pathophysiology of BPH in patients with diabetes could possibly be explained by an increased sympathetic tone and stimulation of prostate growth by insulin 14 .…”

Section: Discussionmentioning

confidence: 99%

Characteristics of recurrent acute urinary retention in BPH patients in the United States: Retrospective analysis of US‐based insurance claims database

et al. 2023

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“…However, AUR as a consequence of neurological etiologies can also be painless, such as those caused by acute spinal cord injury. The etiologies of AUR are myriad, ranging from obstructive, infectious, neurogenic, iatrogenic, and pharmacologic causes 2‐7 . AUR can happen in any population, however, its incidence in males is more than 10‐fold higher than in women, particularly with increased aging.…”

Section: Introductionmentioning

confidence: 99%

“…The etiologies of AUR are myriad, ranging from obstructive, infectious, neurogenic, iatrogenic, and pharmacologic causes. [2][3][4][5][6][7] AUR can happen in any population, however, its incidence in males is more than 10-fold higher than in women, particularly with increased aging. Indeed, studies indicate that benign prostatic hypertrophy (BPH) is the leading cause of AUR in male which accounts for more than 50% of all cases.…”

Section: Introductionmentioning

confidence: 99%

Molecular mechanisms of voiding dysfunction in a novel mouse model of acute urinary retention

et al. 2021

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Acute urinary retention (AUR) is a common urological emergency and affects a significant patient population. The inability to eliminate urine may lead to permanent damage to the bladder’s structure and functioning. However, we know little about the underlying molecular sequelae to the urine retention. To closely mirror the potential high pressures that patients with AUR could experience, we catheterized anesthetized female mice via the urethra and filled the bladder by pumping saline (25 µL/min) into the bladder lumen to 50 cm or 80 cm water pressure. A water column with designated height (50 or 80 cm) was then adjusted to maintain constant pressure in the bladder lumen for 30 minutes. Functional and morphological evaluations were performed from 0 to 24 hours after AUR treatment. Mice exhibited incontinence and overactivity with diminished voiding pressure. Significant injury was confirmed which revealed bladders with disrupted urothelial barrier, edematous lamina propria, and distorted muscle bundles. Bladder smooth muscle (BSM) from pressure‐treated mice have significantly diminished contraction force, suggesting that bladder voiding dysfunction can be attributed to impaired BSM contractility. Indeed, dysregulation of acetylcholine and purinergic signaling pathways were demonstrated, indicating that reduced efficacy of these pathways contributes to impaired BSM contractility. Finally, altered expression of β1‐integrin and extracellular matrix mediated mechanotransduction pathways were detected, suggesting a profound remodeling process. These data demonstrated an easy to perform, quantifiable, and reproducible AUR mouse model, which mimics well the characteristics of human AUR patients, and our data generate new insights into the molecular mechanisms that occur following AUR.

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“…The pathophysiology is related to the mechanical compression of proximal urethra by the incarcerated fibroid and urethral elongation, resulting in intermittent voiding dysfunction. 5 …”

Section: Discussionmentioning

confidence: 99%

Robotic myomectomy for a non-pregnant reproductive age woman with severe acute urinary retention: A case report

Sini¹,

Birowo

Hapsari

et al. 2020

Urology Case Reports

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Urinary retention in non-pregnant reproductive age women is a very rare condition. Hereby, we reported a rare case of acute urinary retention in a non-pregnant reproductive-age woman with hydronephrosis and hydroureter due to a large fibroid. The fibroid had resulted in constant pressure to the urethral sphincter, which causes urinary retention. Robotic myomectomy was performed after insertion of ureteric catheters. To our knowledge, this is the first case report of a robotic surgery being utilised to manage acute urinary retention in a non-pregnant individual due to large fibroid.

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A Case of Female Acute Urinary Retention Presenting to the ED

Cited by 6 publications

References 13 publications

Characteristics of recurrent acute urinary retention in BPH patients in the United States: Retrospective analysis of US‐based insurance claims database

Characteristics of recurrent acute urinary retention in BPH patients in the United States: Retrospective analysis of US‐based insurance claims database

Molecular mechanisms of voiding dysfunction in a novel mouse model of acute urinary retention

Robotic myomectomy for a non-pregnant reproductive age woman with severe acute urinary retention: A case report

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