A Case of Genitourinary Xanthogranulomatous Inflammation

Abstract

A case of xanthogranulomatous salpingitis associated with a little invasive lesion of cyst in a 52-years-old woman is presented. Xanthogranulomatous inflammation is a rare form of chronic inflammation, destructive to the involved organs. It is characteristic of the presence of plasma cells, neutrophils, lymphocytes, lipid-filled macrophages. It is reported that most patients with xanthogranulomatous salpingitis often have a clinical history of pelvic inflammatory disease, endometriosis, etc. Here, we reported a case is with unilateral xanthogranulomatous salpingitis with invasion of cyst.

Rare case of non-healing episiotomy wound: a diagnostic Challenge

“…Various explanations were proposed for the mechanisms responsible for XGI, such as: immunological defect of the macrophage; chronic infection of the urachal diverticulum or cyst; foreign material such as retained suture material; abnormal lipid metabolism and lipid accumulation in a macrophage and gram negative or anerobic bacteria such as in genitourinary tract infections or infection after tubal ligation 6 . Infections with Bacteroides fragilis, Escherichia coli, Proteus vulgaris, and Salmonella typhi were also considered.…”

“…Co-existant factors like bleeding and obstruction may also predispose to this infection. Tissue necrosis can occur as a result of all this, which is followed by the release of cholesterol and other lipids and phagocytosis by the macrophages 6 Majority of the cases of XGI of the FGT belongs to age range 23-72 years (mean age 32 years) 7 and present with the complaints of fever, raised ESR and total leucocyte count. A well-defined mass on ultrasound is seen in most of the cases of XGI, which can be confused with the malignancy.…”

Fallop Tüpleri̇ni̇n Nadi̇r İnflamasyonu: İki̇ Ksantogranülomatöz Salpenji̇t Olgusu

“…Pelvik inflamatuar hastalık etyopatogenezde en başta sorumlu tutulmakla beraber nekroz, kanama veya obstrüksiyon da enflamasyona neden olabilir (1, 2, 5). Bundan başka; endometriozisin, radyoterapinin, uygun olmayan antibiyotik tedavisinin, lipid metabolizma bozukluklarının, immün yetmezliklerin ve intrauterin kontraseptif araçların ksantogranülomatöz salpenjite neden olabileceği bildirilmiştir (2,5,6). Literatürde bildirilen olguların çoğunda endometriozis mevcuttur (7).…”

“…Ksantogranulomatöz inflamasyon, etkilediği organın normal dokusunu yıkıma uğratan, kronik inflamasyonun son derece nadir bir formudur (1,2). Çoğunlukla böbreklerde görülmekle beraber safra kesesi, mide, anorektal bölge, kemik, mesane, testis ve epididimis gibi organlarda da tutuluma neden olabilir.…”

“…Nadir olarak multinükleer dev hücreler de görülebilir (3). Patogenezi hakkında çeşitli teoriler öne sürülmüşse de kesin olarak aydınlatılamamıştır (2). Literatürde çok az sayıda ksantogranulomatöz salpenjit olgusu bildirilmiştir.…”