A case of granular cell tumor of the bladder successfully managed with extraperitoneal laparoscopic surgery

Abstract

Granular cell tumor is a benign neoplasm which frequently occurs in the oral cavity, skin, and subcutaneous tissue. Granular cell tumor of the bladder is an extremely rare disease, and only nine cases have been reported. We present here an additional case of granular cell tumor occurring in the bladder. Unlike the other tumors reported, this tumor extruded into the Retzius' cavity. Therefore, the tumor was successfully excised through extraperitoneal laparoscopic surgery. The patient was free from recurrence 40 months after surgery. The small tumor located in Retzius' cavity could be managed with extraperitoneal laparoscopic surgery.

Soft tissue tumors of the urinary bladder, part I: myofibroblastic proliferations, benign neoplasms, and tumors of uncertain malignant potential

“…Several cases of benign granular cell tumors, as well as a case of malignant granular cell tumor, appear in the medical literature [75][76][77][78][79][80][81]. One case occurred in a patient with neurofibromatosis [79].…”

Granular cell tumour of the ureter: first case reported

“…One case was treated by laparoscopic excision. 4 The malignant type of granular cell tumour of the bladder has been reported in one case. 5 To our knowledge, ours is the first case of granular cell tumour that involves the ureter.…”

Granular cell tumor of the urinary bladder

“…[7,13,14] Because of the predominantly benign course of the GCTs, conservative surgical treatment by transurethral resection taking care to leave clear surgical margins is sufficient and more radical resections are not required. [1][2][3]15] In conclusion, GCT is an unusual lesion of the urinary bladder. To differentiate this benign tumor from more common urothelial lesions, careful histomorphological examination and appropriate immunohistochemical studies are necessary.…”