A Case of Hydrocortisone Sodium Succinate-Induced Asthma

Sunaga, Yasuo; Kurosawa, Motohiro; Nemoto, Toshikazu; Fueki, R; Kobayashi, Setsuo; Kobayashi, Toshio

doi:10.2974/kmj1951.35.565

Cited by 1 publication

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, aciont (Visulex®) is currently in phase II clinical trial for treating uveitis [ 8 , [45] , [46] ]. Other synthetic glucocorticoid corticosteroid analogues include hydrocortisone sodium phosphate (Hydrocortone®1960, 21 ) and prednisolone sodium phosphate (Prednesol/Predsol/Predsolan/Solu-Predalone/Solucort®) ( 20 ), which are also used in combination with sulfacetamide sodium (Vasocidin®1988) and phenoxazoline* [ 9 , [47] , [48] ]. In addition, estramustine phosphate sodium (Emcyt/Estracyt®) ( 22 ) has been approved as an alkylating agent to treat prostatic cancer [ 10 ].…”

Section: Classification Of P (V)-containing Drugsmentioning

confidence: 99%

Development and Clinical Application of Phosphorus-Containing Drugs

Shi³

et al. 2020

Medicine in Drug Discovery

120

View full text Add to dashboard Cite

Phosphorus-containing drugs belong to an important class of therapeutic agents and are widely applied in daily clinical practices. Structurally, the phosphorus-containing drugs can be classified into phosphotriesters, phosphonates, phosphinates, phosphine oxides, phosphoric amides, bisphosphonates, phosphoric anhydrides, and others; functionally, they are often designed as prodrugs with improved selectivity and bioavailability, reduced side effects and toxicity, or biomolecule analogues with endogenous materials and antagonistic endoenzyme supplements. This review summarized the phosphorus-containing drugs currently on the market as well as a few promising molecules at clinical studies, with particular emphasis on their structural features, biological mechanism, and indications.

show abstract