A case of hypophyseal prolactinoma with treatable delusions of dermatozoiasis

Takeda, Masaya; Tanino, Shiro; Nishinuma, Keiji; Matsubayashi, Tsuneo; Yamashita, S.; Nishimura, Taichi

doi:10.1111/j.1600-0447.1985.tb02641.x

Cited by 15 publications

(10 citation statements)

References 12 publications

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“…In contrast, Wilson and Miller found primary DI in only about 8% of cases (344). Most other authors believe that cases of DI secondary to macroscopic brain disorders (organic) are more typical than primary DI (32,78,203,299,315). Four studies suggest that primary DI is more frequent than organic DI but that all forms of secondary DI taken together dominate.…”

Section: Inset 12 Dsm-iv-tr Diagnostic Criteria For Delusional Disormentioning

confidence: 91%

“…Ischemic brain lesions in these patients were seen predominantly in subcortical regions and in temporo-parietal regions after stroke (2,37,68,90,97,195,242,244,278,314). Other case reports linked the origin of symptoms with a brain tumor in the hypophyseal region (30,183,217,219,315) or a craniopharyngioma (333). A potential pathogenetic role of the thalamus in DI was first hypothesized in 1920 (107).…”

Section: Pathophysiology Of DImentioning

confidence: 99%

“…The nosology and correct classification of DI have been controversial since the first description of the syndrome (Inset 10). Ekbom conceptualized the syndrome as a "presenile" involutional (progressive) or organic syndrome (32,78,203,299,315), while other authors saw DI within the spectrum of affective disorders (43,44,289), schizophrenia (138,139), or delusional disorders/paranoia (299). The debate is futile, because "the" DI does not exist.…”

Section: Classification and Types Of DImentioning

confidence: 99%

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Delusional Infestation

Freudenmann

Lepping²

2009

Clin Microbiol Rev

235

367

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SUMMARY This papers aims at familiarizing psychiatric and nonpsychiatric readers with delusional infestation (DI), also known as delusional parasitosis. It is characterized by the fixed belief of being infested with pathogens against all medical evidence. DI is no single disorder but can occur as a delusional disorder of the somatic type (primary DI) or secondary to numerous other conditions. A set of minimal diagnostic criteria and a classification are provided. Patients with DI pose a truly interdisciplinary problem to the medical system. They avoid psychiatrists and consult dermatologists, microbiologists, or general practitioners but often lose faith in professional medicine. Epidemiology and history suggest that the imaginary pathogens change constantly, while the delusional theme “infestation” is stable and ubiquitous. Patients with self-diagnosed “Morgellons disease” can be seen as a variation of this delusional theme. For clinicians, clinical pathways for efficient diagnostics and etiology-specific treatment are provided. Specialized outpatient clinics in dermatology with a liaison psychiatrist are theoretically best placed to provide care. The most intricate problem is to engage patients in psychiatric therapy. In primary DI, antipsychotics are the treatment of choice, according to limited but sufficient evidence. Pimozide is no longer the treatment of choice for reasons of drug safety. Future research should focus on pathophysiology and the neural basis of DI, as well as on conclusive clinical trials, which are widely lacking. Innovative approaches will be needed, since otherwise patients are unlikely to adhere to any study protocol.

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Section: Inset 12 Dsm-iv-tr Diagnostic Criteria For Delusional Disormentioning

confidence: 91%

Section: Pathophysiology Of DImentioning

confidence: 99%

Section: Classification and Types Of DImentioning

confidence: 99%

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Delusional Infestation

Freudenmann

Lepping²

2009

Clin Microbiol Rev

235

367

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“…A 69-year-old woman with hypophyseal prolactinoma presented with hyperprolactinemia and 'dermatozoic' delusions [16] . Treatment with the dopamine agonist bromocriptine, followed by small dose haloperidol, successfully resolved the delusion.…”

Section: Increased Serum Prolactin In Prolactinomas and Delusions Of mentioning

confidence: 99%

Hyperprolactinemia and Delusion of Pregnancy

Ahuja¹,

Vasudev²,

Lloyd³

2007

Psychopathology

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We describe the case of a 44-year-old woman admitted with mania with psychotic symptoms who presented with delusion of twin pregnancy a month after admission, which temporally correlated with hyperprolactinemia secondary to antipsychotic medication. Modification of antipsychotic medication was associated with fall in serum prolactin and disappearance of delusion of pregnancy. In light of this clinically striking temporal association between hyperprolactinemia and delusion of pregnancy, we review the literature to examine the hypothetical relationship. We highlight the clinical significance of examining the various factors, including antipsychotic-induced hyperprolactinemia, which could trigger the development of delusion of pregnancy.

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“…Interestingly, all of the patients with severe radiation damage had Cushing's and diencephalic amnesia have also been reported [6]. Persistent delusions have been described [7]. Visual disease.…”

Section: Neurocognitive Profilementioning

confidence: 99%

Neurobehavioral Functioning of Adults with Pituitary Disease

Meyers¹

1998

Psychother Psychosom

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Neurobehavioral disorders are not infrequent in adults with pituitary disease. The disorders can be due to compression of brain structures important for cognitive and emotional function, effects of hormonal imbalance on sensitive structures, post-surgical disruption of connecting pathways, adverse reactions to medical therapy, and adverse delayed effects of radiation therapy. A multidisciplinary team approach to the treatment of pituitary tumors will allow for the early diagnosis of neurobehavioral disorders and the institution of pharmacologic and behavioral interventions.

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A case of hypophyseal prolactinoma with treatable delusions of dermatozoiasis

Cited by 15 publications

References 12 publications

Delusional Infestation

Delusional Infestation

Hyperprolactinemia and Delusion of Pregnancy

Neurobehavioral Functioning of Adults with Pituitary Disease

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