A case of impetigo herpetiformis in which termination of pregnancy was required

Yao, Xinjing; Zhang, Xiaoxia; Peng, Min; Wang, He; Meng, Yizi; Chen, Ying

doi:10.1177/0300060520933811

Cited by 10 publications

(16 citation statements)

References 12 publications

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“…The risk of complications implies the need for close monitoring and adequate supportive treatment. Early induction of labor, if appropriate, is suggested in the management of severe or refractory IH [ 168 ]. The data regarding treatment of PP of pregnancy are extremely limited.…”

Section: Treatmentmentioning

confidence: 99%

Pustular Psoriasis: From Pathophysiology to Treatment

Genovese

Moltrasio

Cassano³

et al. 2021

Biomedicines

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Pustular psoriasis (PP) is a clinicopathological entity encompassing different variants, i.e., acute generalized PP (GPP), PP of pregnancy (impetigo herpetiformis), annular (and circinate) PP, infantile/juvenile PP, palmoplantar PP/palmoplantar pustulosis, and acrodermatitis continua of Hallopeau (ACH), which have in common an eruption of superficial sterile pustules on an erythematous base. Unlike psoriasis vulgaris, in which a key role is played by the adaptive immune system and interleukin (IL)-17/IL-23 axis, PP seems to be characterized by an intense inflammatory response resulting from innate immunity hyperactivation, with prominent involvement of the IL-36 axis. Some nosological aspects of PP are still controversial and debated. Moreover, owing to the rarity and heterogeneity of PP forms, data on prognosis and therapeutic management are limited. Recent progresses in the identification of genetic mutations and immunological mechanisms have promoted a better understanding of PP pathogenesis and might have important consequences on diagnostic refinement and treatment. In this narrative review, current findings in the pathogenesis, classification, clinical features, and therapeutic management of PP are briefly discussed.

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Section: Treatmentmentioning

confidence: 99%

Pustular Psoriasis: From Pathophysiology to Treatment

Genovese

Moltrasio

Cassano³

et al. 2021

Biomedicines

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“…The literature search identified 83 articles, only 35 were ultimately selected 5–39 . The corresponding results are summarized in Table 2.…”

Section: Resultsmentioning

confidence: 99%

Pustular psoriasis of pregnancy: Clinical and genetic characteristics in a series of eight patients and review of the literature

Ennouri

Bahloul

Sellami

et al. 2022

Dermatologic Therapy

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“…Besides tumor necrosis factor (TNF) alpha blockers such as infliximab and adalimumab, interleukin-12/23(IL-12/23) antagonist ustekinumab and interleukin-17A(IL-17A) antagonist secukinumab have also been used to treat recalcitrant cases, with favorable results [ 34 , 35 ]. PPP usually resolves after delivery; in cases not responding to drug therapy, induction of labor in the third trimester and termination of pregnancy in the second trimester have been proven effective [ 36 , 37 ]. A minimal number of patients have been treated for PPP that started during the first trimester.…”

Section: Discussionmentioning

confidence: 99%

First-Trimester Impetigo Herpetiformis Leads to Stillbirth: A Case Report

Liu

Ali

Lou

et al. 2022

Dermatol Ther (Heidelb)

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Introduction Pustular psoriasis of pregnancy (PPP), also known as impetigo herpetiformis (IH), is a rare variant of generalized pustular psoriasis (GPP) in pregnancy. It typically occurs in the third trimester and is a life-threatening condition for both the pregnant mother and the fetus if not diagnosed and treated promptly. Drug-induced PPP has been reported in sporadic case reports. Here we present a case of first-trimester PPP occurring after applying drugs including chloroquine, which we consider a possible culprit triggering the disease. Case report A 29-year-old female was admitted to our department at 45 days gestation with sudden onset of fever and widespread erythematous pustules for 9 days. She had been on medications including hydroxychloroquine before onset. The eruptions and systemic symptoms were controlled with high-dose systemic steroids; however, she was detected to have a stillbirth, and underwent dilation and curettage of the uterine. At the latest follow-up about 2 years after her admission, she reported to have delivered a healthy baby about 1 month previously. Conclusions Chloroquine has potential to lead to PPP in the first trimester of pregnancy. Further studies are warranted to investigate the etiology and treatment of PPP to facilitate early recognition and optimal management of this relatively rare dermatosis in pregnancy.

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A case of impetigo herpetiformis in which termination of pregnancy was required

Cited by 10 publications

References 12 publications

Pustular Psoriasis: From Pathophysiology to Treatment

Pustular Psoriasis: From Pathophysiology to Treatment

Pustular psoriasis of pregnancy: Clinical and genetic characteristics in a series of eight patients and review of the literature

First-Trimester Impetigo Herpetiformis Leads to Stillbirth: A Case Report

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