A case of intra-abdominal abscess due to sphingomonas paucimobilis in a patient on peritoneal dialysis: A case report and review of literature

Lim, Chiao Yuen; Jackson, Tan

doi:10.4103/ijn.ijn_271_19

Cited by 5 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 Various case reports showing different infection sites of this organism are documented in literature like a splenic abscess, meningitis, osteomyelitis, secondary septic arthritis, bacteremia with septic pulmonary emboli, intra-abdominal abscess in a patient undergoing peritoneal dialysis, bacteremia outbreak in dialysis room among those using a common dialysis catheter, and paucimobilis fulminant keratitis. 2,[5][6][7][8][9][10] This case report is the second case of splenic abscess by S. paucimobilis documented in the literature, and probably the first case report of such an abscess in an immunocompetent host. The strain identified in the blood culture is susceptible to piperacillin/tazobactam, ceftriaxone, cefepime, imipenem, meropenem, amikacin, ciprofloxacin, and tigecycline.…”

Section: Discussionmentioning

confidence: 67%

Multiple hepatosplenic abscesses in an immunocompetent host

Hirapara

Bhende²,

Rangwala³

et al. 2022

Int J Res Med Sci

View full text Add to dashboard Cite

Sphingomonas paucimobilis, a gram-negative organism, mainly infects immunocompromised hosts due to its low virulence. Patients with such an infection usually have contact with healthcare. Meningitis, peritonitis, visceral abscess, septic arthritis, septicemia, post-traumatic endophthalmitis, and keratitis are among the documented complications of Sphingomonas paucimobilis infection. Such an infection is rarely seen in the literature as the one causing splenic and liver abscess and that too in an immunocompetent host. We present a case of a 23-year-old immunocompetent male, who presented with fever and other constitutional symptoms with recent onset of abdominal pain and fullness. Splenic and liver abscesses were detected on radiology with the growth of only Sphingomonas on blood culture and negative reports for other organisms excluding the differentials, proving S.mobilis being the cause of the abscesses. The patient was managed on broad-spectrum antibiotics and additional medications for symptomatic relief. The patient gradually improved over 7 days of hospitalization. This case report mainly focuses on Sphingomonas paucimobilis infection, which is rarely seen and documented, and surprisingly in an immunocompetent host causing life-threatening infections and abscesses. Even though it’s a rare and a low virulence organism, such a presentation must not be overlooked. A regular and focused laboratory workup for detection and management, with adequate antibiotic treatment, is a must to avoid a poor prognosis.

show abstract

Section: Discussionmentioning

confidence: 67%

Multiple hepatosplenic abscesses in an immunocompetent host

Hirapara

Bhende²,

Rangwala³

et al. 2022

Int J Res Med Sci

View full text Add to dashboard Cite

show abstract

“…There are seven references for case reports and literature reviews included in our study ( Figure 2 ) [ 38 , 39 , 40 , 41 , 42 , 43 , 44 ]. We analyzed all the references cited in these seven references.…”

Section: Resultsmentioning

confidence: 99%

“…When the literature review was not clearly systematized, we considered only the case report of the study [ 42 ]. We retrieved for further analyses 89 cases from the seven case reports and literature review references [ 38 , 39 , 40 , 41 , 42 , 43 , 44 ]. After screening the rest of the 42 references, we retrieved 358 cases.…”

Section: Resultsmentioning

confidence: 99%

The Gram-Negative Bacilli Isolated from Caves—Sphingomonas paucimobilis and Hafnia alvei and a Review of Their Involvement in Human Infections

Ionescu

Neagoe

Crăciun

et al. 2022

IJERPH

View full text Add to dashboard Cite

The opportunistic infections with Gram-negative bacilli are frequently reported. The clinical studies are focused on the course of human infectious and very often the source of infection remain unclear. We aim to see if the Gram-negative bacilli isolated from a non-contaminated environment—the caves—are reported in human infections. Eleven samples were collected from six Romanian caves. We used the standard procedure used in our clinical laboratory for bacterial identification and for antibiotic susceptibility testing of the cave isolates. Out of the 14 bacterial strains, three isolates are Gram-negative bacilli—one isolate belong to Hafnia alvei and two strains belong to Sphingomonas paucimobilis. We screened for the published studies—full-text original articles or review articles—that reported human infections with S. paucimobilis and H. alvei. Data sources—PubMed and Cochrane library. We retrieved 447 cases from 49 references—262 cases (58.61%) are S. paucimobilis infections and 185 cases (41.39%) are H. alvei infections. The types of infections are diverse but there are some infections more frequent; there are 116 cases (44.27%) and many infections of the bloodstream with S. paucimobilius (116 cases) and 121 cases (65.41%) are urinary tract infections with H. alvei. The acquired source of the bloodstream infections is reported for 93 of S. paucimobilis bloodstream infections—50 cases (43%) are hospital-acquired, and 40 cases (37%) are community-acquired. Most of the infections are reported in patients with different underlying conditions. There are 80 cases (17.9%) are reported of previously healthy persons. Out of the 72 cases of pediatric infections, 62 cases (86.11%) are caused by S. paucimobilis. There are ten death casualties—three are H. alvei infections, and seven are S. paucimobilis infections.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Ventilation pneumonia, [14] adenitis, myositis, [15] urinary tract infections, acute enteritis, [16] and abdominal abscesses associated with peritonitis have also been reported. [17] In only 1 case published in 1987, S paucimobilis was identified in a splenic abscess associated with sepsis caused by Clostridioides difficile. [18] Our literature research reported no other case report of splenic abscess caused by S paucimobilis.…”

Section: Discussionmentioning

confidence: 99%

Sphingomonas paucimobilis - a rare cause of splenic abscesses

et al. 2022

View full text Add to dashboard Cite

Rationale: Infections with Sphingomonas paucimobilis are rarely described in the literature and can be community-acquired or associated with healthcare, especially in patients with chronic conditions (e.g., diabetes mellitus), malignancies, or other causes of immunosuppression, except in people without comorbidities. We present the case of a patient with diabetes mellitus and hypertension diagnosed during a routine evaluation, with splenic abscess caused by S paucimobilis . Our literature search revealed no other case report of splenic abscess caused only by S paucimobilis . Patient concerns: We present the case of a 55-year-old Caucasian man with type 2 diabetes mellitus and hypertension. Diagnosis: Thoraco-abdominal computed tomography revealed splenomegaly of 20X16X18 cm, with a homogeneous subcapsular hypodense collection, with a mass effect on the left hemidiaphragm. Interventions: The patient underwent surgical intervention and S paucimobilis was isolated on blood agar. Outcome: The patient received treatment with ciprofloxacin (500 mg twice daily) for 14 days, with favorable outcomes. Lessons: S paucimobilis , a low-virulence bacterium, can cause community-acquired or nosocomial infections. Visceral localizations, usually symptomatic, can evolve rapidly, and the diagnosis is associated with complications or, as in our case, with careful investigation of some changes in laboratory investigations.

show abstract

A case of intra-abdominal abscess due to sphingomonas paucimobilis in a patient on peritoneal dialysis: A case report and review of literature

Cited by 5 publications

References 16 publications

Multiple hepatosplenic abscesses in an immunocompetent host

Multiple hepatosplenic abscesses in an immunocompetent host

The Gram-Negative Bacilli Isolated from Caves—Sphingomonas paucimobilis and Hafnia alvei and a Review of Their Involvement in Human Infections

Sphingomonas paucimobilis - a rare cause of splenic abscesses

Contact Info

Product

Resources

About