A case of intramuscular xanthelasma palpebrarum found during blepharoplasty

Abstract

Xanthelasma palpebrarum is the most common cutaneous xanthoma found on the medial side of the eyelid. The typical lesion is usually a flat and yellowish plaque on the skin. However, we report on a unique case of intramuscular xanthoma found during blepharoplasty for the correction of ptosis. A 53-year-old male patient visited our department with a complaint of a ptotic eyelid. He was concerned about the cosmetic appearance and the uncomfortable feeling while opening his eyes, and wanted these problems to be solved. A yellowish plaque of about 0.3 × 0.3 cm in size was found in the orbicularis oculi muscle during the surgery. The lesion was excised and xanthelasma was confirmed with biopsy. We have found this specific case of xanthelasma palpebrarum in the only muscle. Therefore, a careful approach to clinical and histologic examination and imaging is required for patients with these lesions.

Clinical association between serum cholesterol level and the size of xanthelasma palpebrarum

“…Considering the pathogenesis, leakage of low-density lipoprotein (LDL) from the capillaries is an important aspect of the disease etiology [ 3 , 4 ]; mechanical movement and friction, heat, and inflammatory responses accelerate the leakage of LDL. These factors are prevalent around the eyelids, explaining the higher incidence of xanthelasma appearance compared other parts of the body [ 5 ].…”