A Case of Late-Onset Genital Apocrine Chromhidrosis

A Case of Eccrine Chromhidrosis Due to Multivitamin Use

“…Apocrine chromhidrosis is more common after puberty, even though late-onset cases (1,3). In addition, apocrine chromhidrosis is a chronic process that is affected by hormone changes and it is not expected to regress with increased water consumption as it regressed in our case (1).…”

“…Quinine, bisacodyl, clofazimine, methylene blue, fluorescein, copper, beta carotene, silver, rifampin etc. are known to cause eccrine chromhidrosis (1)(2)(3)(4). Since our patient's complaints appeared after using multivitamins containing copper and beta carotene, decreased by increasing water consumption, and consisted of blue sweat on the front of the chest in contradistinction to apocrine chromhidrosis, we considered our case as an eccrine chromhidrosis.…”

“…Chromhidrosis is a rare condition that occurs when apocrine or eccrine sweat glands produce colored sweat. It is more common especially after puberty due to increased hormone secretion (1,3).…”

“…Eccrine chromhidrosis may occur by some water-soluble dyes that enter systemic circulation, as a result of drug metabolism such as quinine, bisacodyl, clofazimine etc. or due to contamination of micro-organisms and rarely hyperbilirubinemia (1)(2)(3). The first and most important step for diagnosis of eccrine chromhidrosis is clinical evaluation.…”