“…The incidence of atrial fibrillation (AF) and deep vein thrombosis/pulmonary embolism (DVT/PE) has increased in the last decades as a consequence of global aging and the refinement of diagnostic techniques; thus, the consumption of anticoagulant drugs has increased signifi cantly. [1,2] Prescriptions of direct oral anticoagulants (DOACs) have overtaken those of vitamin K antagonists (VKA) since the mid-2010s. [3] Consequently, the incidence of these drugs' side eff ects has also increased; the most relevant side effect in terms of morbidity and mortality is bleeding.…”