A Case of Multifocal Idiopathic Fibrosclerosis With Cutaneous Involvement

Ayli, Elias E.; Mutasim, Diya F.

doi:10.1001/archdermatol.2012.2424

Cited by 3 publications

(10 citation statements)

References 3 publications

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“…MIF is a fibrosing disorder described as part of the IgG4 spectrum of diseases, but without elevation of IgG4 in serum or IgG4-positive plasma cell infiltrate on biopsy, as previously reported by Ayli and Mutasim. 3,4 A suggested definition of MIF is 2 or more areas of progressive fibrosclerosis present in the same patient. 3 The disease's manifestations are protean and include Riedel thyroiditis, retroperitoneal fibrosis, sclerosing pancreatitis, pseudotumor of the orbit, and cholangitis.…”

Section: Discussionmentioning

confidence: 99%

“…3,4 A suggested definition of MIF is 2 or more areas of progressive fibrosclerosis present in the same patient. 3 The disease's manifestations are protean and include Riedel thyroiditis, retroperitoneal fibrosis, sclerosing pancreatitis, pseudotumor of the orbit, and cholangitis. [1][2][3][4] To our knowledge, only 1 previous case of MIF with cutaneous involvement has been reported.…”

Section: Discussionmentioning

confidence: 99%

“…3 The disease's manifestations are protean and include Riedel thyroiditis, retroperitoneal fibrosis, sclerosing pancreatitis, pseudotumor of the orbit, and cholangitis. [1][2][3][4] To our knowledge, only 1 previous case of MIF with cutaneous involvement has been reported. 3 Histopathologic features of MIF include dense interstitial lymphoplasmacytic infiltration, perivascular sclerosis, fibrous tissue with scant inflammation, and vasculitis.…”

Section: Discussionmentioning

confidence: 99%

“…2 To date, only 1 case of MIF with cutaneous involvement has been reported. 3 We report a case of MIF with cutaneous and retroperitoneal involvement, the cutaneous manifestations of which were successfully treated with intralesional triamcinolone.…”

Section: Introductionmentioning

confidence: 99%

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Cutaneous involvement in a case of multifocal idiopathic fibrosclerosis

2020

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cutaneous involvement in a case of multifocal idiopathic fibrosclerosis

2020

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“…Dear Editor, Multifocal fibrosclerosis (MFS) or multifocal idiopathic fibrosclerosis (MIF) is a rare disease causing fibrosis in multiple organs. 1 MFS was used in 1967 for family cases having retroperitoneal fibrosis, mediastinal fibrosis, sclerosing cholangitis, Riedel's thyroiditis, and pseudotumor of the orbit. 2 After Hamano et al…”

Section: Non-immunoglobulin G4-related Multifocal Fibrosclerosis Presenting Generalized Morphea-like Skin Lesionsmentioning

confidence: 99%

Non‐immunoglobulin G4‐related multifocal fibrosclerosis presenting generalized morphea‐like skin lesions

Chiba

Mizuashi

Tamabuchi

et al. 2021

The Journal of Dermatology

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Clinical presentation and organ-based outcomes of Multifocal fibrosclerosis: A systematic review

et al. 2023

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Objectives: Multifocal fibrosclerosis is a rare disorder causing progressive fibrosis of multiple organ systems. Existing data on the disease show that there are multiple manifestations of the disease, with different outcomes. However, quantitative data are scarce, prompting the need for our investigation. Method: A comprehensive systematic review was performed from inception to November 16, 2022, with the restriction of English language, not including review articles. Article screening and extraction was performed independently, and shortlisted articles were assessed for bias. Analysis was performed using SPSS Version 25 (IBM® SPSS® Statistics; Chicago, IL, USA). Data were presented as frequencies and percentages, with a confidence interval of 95%. Result: This review included 134 patients, with 78 (58.2%) males. Mean age was 53.6 years and included two pediatric patients. The most common comorbidity was diabetes (9.7%). Prevalent presenting symptoms included pain (47.8%) and swelling (35.1%). A mean of 2.51 organs or anatomical sites was affected, retroperitoneum (64.2%) being most affected. The pancreas (30.0%) and digestive system (47.0%) were the organs/organ systems most affected. Patients had favorable outcomes in 79.1% of cases, 87.3% had no relapse, and 91.8% of patients survived the condition. Conclusion: The findings in this study provide a quantitative measurement of the demographics, presentations, organ manifestations, and outcomes of multifocal fibrosclerosis. We found the disease to be prevalent in males in Japan or the United States, with the abdomen and its organs being commonly involved.

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A Case of Multifocal Idiopathic Fibrosclerosis With Cutaneous Involvement

Cited by 3 publications

References 3 publications

Cutaneous involvement in a case of multifocal idiopathic fibrosclerosis

Cutaneous involvement in a case of multifocal idiopathic fibrosclerosis

Non‐immunoglobulin G4‐related multifocal fibrosclerosis presenting generalized morphea‐like skin lesions

Clinical presentation and organ-based outcomes of Multifocal fibrosclerosis: A systematic review

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