A case of myeloid sarcoma with duodenal involvement presenting with exrtahepatic cholestasis

Abstract

Myeloid sarcoma (MS) is a hematologic malignancy composed of myeloblasts or immature myeloid cells presenting in the extramedullary region. MS frequently involves bone, soft tissue, skin, lymph nodes, as well as the genitourinary and gastrointestinal systems. We wanted to present a case of MS presenting with duodenal involvement. A 22-year-old male patient presented with abdominal pain and jaundice. Laboratory values of total bilurubin: 7.75 mg/dl, indirect bilurubin: 6.7 mg/dl, GGT: 215 U/L. ERCP showed dilated choledochal dilatation with migrated stent and stenosis at the distal end. The existing stent was removed and a 10 FR 12 cm biliary plastic stent was placed proximal to the stenosis. Since hyperemic, erosion lesions were observed in the mouth of Oddi and duodenum, biopsies were taken from that region. The biopsy result was reported as primary duodenal myeloid sarcoma. MS should be considered in gastrointestinal lesions.