A case of NDM-1-producing Acinetobacter baumannii transferred from India to Japan

Nakazawa, Yozo; Ryoko,; Tamura, Taku; Hoshina, Tokio; Tamura, Kaori; Kawano, Sayaka; Kato, Takumi; Sato, Fumiya; Horino, Tetsuya; Yoshida, Masaki; Hori, Seiji; Sanui, Masamitsu; Ishii, Yoshikazu; Tateda, Kazuhiro

doi:10.1007/s10156-012-0469-5

Cited by 24 publications

(9 citation statements)

References 8 publications

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“…Indeed, NDM-1 was first reported in India from Enterobacteriaceae and then in A. baumannii [126,127]. Other reports are from different European countries and from China, Japan, Kenya, Brazil, Algeria and Syria [128][129][130][131][132][133][134][135][136][137]. An outbreak of NDM-1-producing A. baumannii, belonging to ST85, was recently reported in France [138], underscoring the growing concern related to the spread of these isolates in Europe.…”

Section: Acinetobacter Baumanniimentioning

confidence: 99%

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology

Potron

Poirel

Nordmann

2015

International Journal of Antimicrobial Agents

606

460

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Multidrug resistance is quite common among non-fermenting Gram-negative rods, in particular among clinically relevant species including Pseudomonas aeruginosa and Acinetobacter baumannii. These bacterial species, which are mainly nosocomial pathogens, possess a diversity of resistance mechanisms that may lead to multidrug or even pandrug resistance. Extended-spectrum ␤-lactamases (ESBLs) conferring resistance to broad-spectrum cephalosporins, carbapenemases conferring resistance to carbapenems, and 16S rRNA methylases conferring resistance to all clinically relevant aminoglycosides are the most important causes of concern. Concomitant resistance to fluoroquinolones, polymyxins (colistin) and tigecycline may lead to pandrug resistance. The most important mechanisms of resistance in P. aeruginosa and A. baumannii and their most recent dissemination worldwide are detailed here.

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Section: Acinetobacter Baumanniimentioning

confidence: 99%

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology

Potron

Poirel

Nordmann

2015

International Journal of Antimicrobial Agents

606

460

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“…The first imported NDM-1-producing bacteria was isolated in 2007 in Germany [126], followed by two isolates in 2008 in the United Kingdom [7] and the Netherlands, respectively [127]. In most of the cases, patients had connections to other countries or regions such as the Indian subcontinent (n=121) [7,57,104,106,109,[123][124][125], the Balkan (n=11) [8,112,131,[163][164][165][166][167][168] , Africa (n=10) [117,123,160,165,[169][170][171][172][173][174] , the Middle East (n=6) [175][176][177][178], and East Asia (n=5) [179,180] . The patients originated from these areas, had spent time or been hospitalised there, or they might have been secondarily linked to other hospitalised patients who had recently returned from these areas.…”

Section: Distribution Of Autochthonous Case Reports Of New Delhi Metamentioning

confidence: 99%

New Delhi Metallo-beta-lactamase around the world: An eReview using Google Maps

et al. 2014

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Gram-negative carbapenem-resistant bacteria, in particular those producing New Delhi Metallo-betalactamase-1 (NDM-1), are a major global health problem. To inform the scientific and medical community in real time about worldwide dissemination of isolates of NDM-1-producing bacteria, we used the PubMed database to review all available publications from the first description in 2009 up to 31 December 2012, and created a regularly updated worldwide dissemination map using a web-based mapping application. We retrieved 33 reviews, and 136 case reports describing 950 isolates of NDM-1-producing bacteria. Klebsiella pneumoniae (n= 359) and Escherichia coli (n=268) were the most commonly reported bacteria producing NDM-1 enzyme. Several case reports of infections due to imported NDM-1 producing bacteria have been reported in a number of countries, including the United Kingdom, Italy, and Oman. In most cases (132/153, 86.3%), patients had connections with the Indian subcontinent or Balkan countries. Those infected were originally from these areas, had either spent time and/ or been hospitalised there, or were potentially linked to other patients who had been hospitalised in these regions. By using Google Maps, we were able to trace spread of NDM-1-producing bacteria. We strongly encourage epidemiologists to use these types of interactive tools for surveillance purposes and use the information to prevent the spread and outbreaks of such bacteria.

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“…Facing with this serious situation, we are in urgent need of new therapeutic options. [ 87 ] One approach to combat this growing problem is the use of combination drug antibiotic adjuvant therapy. Antibiotic adjuvants include not only antibiotics but also other bioactive molecules according to the study of Lindsay and Gerard.…”

Section: Introductionmentioning

confidence: 99%

New Delhi Metallo-β-Lactamase-Mediated Carbapenem Resistance

Wei

Yang

et al. 2015

Chinese Medical Journal

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Objective:To review the origin, diagnosis, treatment and public health concern of New Delhi metallo-β-lactamase (NDM)-producing bacteria.Data Sources:We searched database for studies published in English. The database of PubMed from 2007 to 2015 was used to conduct a search using the keyword term “NDM and Acinetobacter or Enterobacteriaceae or Pseudomonas aeruginosa.”Study Selection:We collected data including the relevant articles on international transmission, testing methods and treatment strategies of NDM-positive bacteria. Worldwide NDM cases were reviewed based on 22 case reports.Results:The first documented case of infection caused by bacteria producing NDM-1 occurred in India, in 2008. Since then, 13 blaNDM variants have been reported. The rise of NDM is not only due to its high rate of genetic transfer among unrelated bacterial species, but also to human factors such as travel, sanitation and food production and preparation. With limited treatment options, scientists try to improve available therapies and create new ones.Conclusions:In order to slow down the spread of these NDM-positive bacteria, a series of measures must be implemented. The creation and transmission of blaNDM are potentially global health issues, which are not issues for one country or one medical community, but for global priorities in general and for individual wound care practitioners specifically.

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A case of NDM-1-producing Acinetobacter baumannii transferred from India to Japan

Cited by 24 publications

References 8 publications

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology

New Delhi Metallo-beta-lactamase around the world: An eReview using Google Maps

New Delhi Metallo-β-Lactamase-Mediated Carbapenem Resistance

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