A case of neck xanthogranulomatous inflammation‐suspected malignant tumor

Abstract

Xanthogranulomatous inflammation (XGI) is an uncommon chronic inflammatory disease. A 59‐year‐old male presented with a neck mass which had been diagnosed as an undifferentiated carcinoma. From CD68 staining, XGI was confirmed. It is important to consider the possibility of XGI for a neck mass mimicking a malignant tumor.

Branchial Cleft Cyst Associated with Xanthogranulomatous Inflammation – An Unusual Case

“…[ 4 ] Very few cases are described in the head and neck and uniquely restricted to some cystic lesions and masses in the neck including Rathke’s cleft cyst in pituitary gland, colloid cyst in 3 rd ventricle, branchial cleft cyst, and thyroglossal duct cyst. [ 3 4 5 ] Our case is the second case of branchial cleft cyst with XGI. Several theories have been proposed for the association of XGI with cystic lesions in head and neck but actual relationship is still largely unknown.…”

“…[ 2 ] Xanthogranulomatous inflammation (XGI) is a mass forming lesion characterised by foamy histiocytes, giant cells, and granuloma formation. [ 3 4 5 ] This type of inflammation is rarely described in the head-and-neck area and its association with branchial cleft cyst is unique.…”

Xanthogranulomatous inflammation of the lower jaw bone: a rare case report

“…Xanthogranulomatous inflammation (XGI) is an uncommon type of chronic inflammation histologically characterized by foamy histiocytes and giant cells. The most common sites of occurrence are the kidneys and gallbladder 1 . The etiology remains controversial, and involvement of the lower jawbone is rare.…”