A Case of Neurilemoma of Sigmoid Colon

Kitajima, Masayuki; Takita, Naohito; Yamaguchi, Hirohiko; Kasamaki, Shinji; Sakamoto, Kazuhiro; Kamano, Toshiki

doi:10.3919/jjsa.66.1972

Cited by 5 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Spiral-like forms consisting of densely arrayed spindle-shaped tumor cells, palisade arrangements and loose reticular networks of tumor cells can be cited as histological features and Verocay corpuscles and lymphoid cuff are characteristic [4, 5, 6]. In addition, blood vessels in tumors show hyalinization of the wall and clot formation.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis is considered to be definite if the proliferation of spindle cells is histopathologically observed through HE staining and if both KIT (CD117) and CD34 are stained negative and S-100 protein is stained positive in immunohistochemical staining [ 3 ]. Spiral-like forms consisting of densely arrayed spindle-shaped tumor cells, palisade arrangements and loose reticular networks of tumor cells can be cited as histological features and Verocay corpuscles and lymphoid cuff are characteristic [ 4 , 5 , 6 ]. In addition, blood vessels in tumors show hyalinization of the wall and clot formation.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Case of Benign Schwannoma of the Transverse Colon with Granulation Tissue

Tsunoda

Kato

Sakamoto

et al. 2009

Case Rep Gastroenterol

View full text Add to dashboard Cite

Schwannomas occurring in the gastrointestinal tract are rare, and among them, schwannomas of the large intestine are extremely rare. In this paper, we report a case of a macroscopically atypical schwannoma of the transverse colon. The case is a female aged 67. Stool occult blood test was positive, and colonoscopy revealed a protruded lesion resembling a type 1 carcinoma measuring 4 cm with a reddish and uneven surface on the transverse colon. The surface was smooth and lobulated in observation with indigo carmine spray, and granulation tissue was revealed by biopsies. CT of the abdomen showed an irregular mass, and clinical examinations could not rule out malignancy. Therefore, partial transverse colectomy with peripheral lymph node dissection was performed. Histologically, proliferation of spindle cells was observed originating from the muscularis propria, and most of the upper part of the lesion was replaced by granulation tissue. In immunohistochemical staining, S-100 protein and NSE were positive while KIT, CD34, desmin and smooth muscle actin were negative, and the tumor was therefore diagnosed to be a schwannoma. In addition, since the MIB-1 labeling index was low and virtually no mitosis was observed, it was diagnosed as benign tumor.

show abstract

Section: Discussionmentioning

confidence: 99%