A case of nodular fasciitis that was difficult to distinguish from sarcoma

Nagano, Hisato; Kiyosawa, Tomoharu; Aoki, Shimpo; Azuma, Ryuichi

doi:10.1016/j.ijscr.2019.10.036

Cited by 16 publications

(21 citation statements)

References 21 publications

(25 reference statements)

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“…Plaza et al [13] reported that two thirds of their cases had been misdiagnosed as sarcoma. A different study showed a diagnostic dilemma when clinical findings suggestive of nodular fasciitis which turned out to be a peripheral nerve sheath tumor [14] . This case highlights the diagnostic dilemma encountered and the benefit of excisional biopsy and immunohistochemistry [15] in aiding our diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Malignant primary intraosseus synovial sarcoma – a rare case report

Iseko¹,

Awoyemi²,

Essien³

et al. 2022

Radiology Case Reports

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Primary intraosseous synovial sarcoma is an extremely rare malignancy that occurs primarily in young adults. We present a case of a primary intraosseous synovial sarcoma of the right distal ulna in a 19-year-old female. It has a propensity to mimic other radiologic and pathologic diagnosis. Histopathology after a surgical excisional biopsy with a wide margin plus adjunct radio and chemotherapy are necessary to improve prognosis.

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Section: Discussionmentioning

confidence: 99%

Malignant primary intraosseus synovial sarcoma – a rare case report

Iseko¹,

Awoyemi²,

Essien³

et al. 2022

Radiology Case Reports

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“…NF may gradually disappear without surgical intervention. 17 Some studies [19][20][21] Compared with conventional skin imaging methods, with the ability of visualization of wholly morphological features, HR-MRI can easily show details of tumors simultaneously, which indicates its high clinical significance for the diagnosis of skin tumors. 22 Dynamic contrast-enhanced (DCE)-MRI can reflect perfusion and vascular permeability of living tissues based on the dynamic changes in signal intensity after contrast agent injection.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and differential diagnosis of dermatofibrosarcoma protuberans: Utility of high‐resolution dynamic contrast‐enhanced (DCE) MRI

Zhu

Huang

et al. 2022

Skin Research and Technology

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Background Dermatofibrosarcoma protuberans (DFSP) is a kind of low‐grade malignant spindle cell neoplasm, the diagnosis, and treatment, which have markedly attracted clinicians’ attention for its repeated recurrence. High‐resolution magnetic resonance imaging (HR‐MRI) has shown unique capabilities in diagnosis of various cutaneous tumors. Materials and methods Data of 29 patients with clinically suspected DFSPs and undergoing dynamic contrast‐enhanced (DCE) HR‐MRI preoperatively were prospectively collected. The HR‐MRI qualitative features were evaluated and compared. The DCE‐associated quantitative parameters and the time‐signal intensity curve (TIC) types were provided using DCE sequences. Results A total of 7 DFSPs, nine dermatofibromas (DF, including four cases of cellular variant [CDF]), 12 keloids, and one nodular fasciitis were enrolled. DFSP showed the largest major diameter and the deepest depth. Five DFSPs (71.4%) showed ill‐defined margins as well as infiltration of peripheral adipose. All DFSPs showed irregular shape. Most DFSPs presented hyperintensity on T2WI (71.4%) and iso‐intensity on T1WI (85.7%). Six cases (85.7%) had significant enhancement, and six cases (85.7%) had homogeneous enhancement. There were significant differences of Ktrans, Kep, Ve and iAUC values among DFSPs, DFs, and keloids, and DFSP had the highest values for these parameters. Six DFSPs (85.7%) and four CDFs (100%) showed type‐III TICs, while the other lesions showed type‐Ⅰor type‐Ⅱ TICs. Conclusions DCE‐HR‐MRI could show the growth characteristics of DFSPs, which was of great value for the diagnosis and differential diagnosis of DFSPs and was helpful for the determination of treatment options, thereby to improve the prognosis of patients.

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“…NF commonly appears rapid growth. The most common sites are the upper limbs [2], trunk [3], head [4] and neck [5]. Sometimes, such as salivary glands [6], breast [7], mesentery [8], and vulva [9] may be involved where were unusual locations.…”

Section: Introductionmentioning

confidence: 99%

Intratracheal Nodular Fasciitis: a Rare Lesion Case Report

Zhang

Cao

Liu

et al. 2022

Preprint

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Nodular fasciitis is a benign proliferation of myofibroblasts that usually arises in subcutaneous tissues of the trunk, neck, head, and upper extremities of young to middle-aged adults. It is not reported to arise in the intratracheal. We present a patient with chest tightness and asthma for three months. Chest computed tomography showed no displayed of left bronchus. The trachea of the left main bronchus was blocked by organisms under bronchoscope. The organisms were extracted and pathologically diagnosed as a rare, benign, intratracheal nodular fasciitis. One month later, the patient relapsed again and underwent resection.

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A case of nodular fasciitis that was difficult to distinguish from sarcoma

Abstract: HighlightsNodular fasciitis is difficult to distinguish from sarcoma.Clinical and pathological findings may not correspond, as in our case.If sarcoma cannot be excluded, treatment should consider the risk of malignancy.

Cited by 16 publications

References 21 publications

Malignant primary intraosseus synovial sarcoma – a rare case report

Malignant primary intraosseus synovial sarcoma – a rare case report

Diagnosis and differential diagnosis of dermatofibrosarcoma protuberans: Utility of high‐resolution dynamic contrast‐enhanced (DCE) MRI

Intratracheal Nodular Fasciitis: a Rare Lesion Case Report

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