“…In the largest series to date (15 patients), a 93% union rate was reported after several different treatments had been performed, including fixation with Kirschner wires, plates, intramedullary nailing and an external fixator with or without a bone autograft (Di Gennaro, 2017). Other smaller series reported less consistent union rates, ranging from 60% to 100%, with the use of traditional treatment methods for non-complex cases (Adamczyk and Riley, 2005; Ballal et al., 2009; Looi et al., 2017). For difficult scenarios, including nonunion related to bone tumours, large bone defects, infection, long-standing nonunions and previous failed treatment, the use of vascularized bone grafts have significantly enhanced union rates (Cano-Luís et al., 2018; Ruiz-Moya et al., 2019).…”