A case of ossifying fibroma of the frontal sinus

Abstract

Ossifying fibroma is a rare benign tumor of the nasal cavity and the paranasal sinus, and is easily misdiagnosed. In the present study, we report the clinical data in the case of a 46-year-old female patient, treated due to 5-day forehead swelling accompanied by dizziness. CT examination revealed dilation of the right frontal sinus, bone wall integration, dense masses in the cavity, multiple punctate calcification foci internally and no nasal obstruction, nasal mucus or epistaxis. After hospitalization, a right frontal sinus fenestration and tumor resection plus nasofrontal duct reconstruction combined with nasal endoscopic frontal recess open surgery was conducted under general anesthesia. Following the tumor resection, the frontal sinus bone lamella was reset and fixed with a titanium bone fixation set. The postoperative pathological diagnosis was of ossifying fibroma. At the postoperative 5-year follow-up there was no tumor recurrence and nasal endoscopy revealed an unobstructed nasofrontal duct opening.

Ossifying Fibroma of Nasal Cavity: A Rare Case Report

“…It may invade the eye socket, skull base and calvarium and may present with related symptoms, and its malignancy rate is (0.4-0.5%). As per the studies, it seems to induce by repetitive surgery or chemotherapy [11]. Regarding the age, rapid progression of the lesion and the radiographic features, the case bears similarity with JOF.…”

“…Patient needs to undergo redo surgery on recurrence. Radiotherapy and chemotherapy are not advised as it may transform the lesion into malignancy like osteosarcoma [11].…”

Fibro-Osseous Lesion of the Nose and Paranasal Sinus: A Retrospective Study With Literature Review

“…Sun et al reported on a 46-year-old female patient with ossifying fibroma [17]. CT scan showed dilation of the right frontal sinus and dense masses in the cavity.…”