A Case of Ossifying Papillary Renal Cell Carcinoma

Case 237: Renal Cell Carcinoma with Osseous Metaplasia

“…As for xanthogranulomatous pyelonephritis, although nephrectomy is frequently necessary, conservative management with aggressive antibiotic therapy is an option in selected patients, especially those with focal disease (1). attenuation area of fat attenuation observed on CT images is suggested to resemble bone architecture, where a peripheral calcified cortical bony component surrounds a noncalcified central fibrofatty medullary space (8) and is compatible with features of osseous metaplasia seen at microscopic examination, where the ossified component is seen adjacent to the fibrofatty component (3,8). We made our diagnosis on the basis of this imaging feature.…”

“…Although it is a classic radiologic teaching that a renal mass with macroscopic fat attenuation at CT is virtually diagnostic of angiomyolipoma, there are a small number of other diagnoses that can also present with this feature (2-7). Renal cell carcinoma with osseous metaplasia is an important entity to consider when confronted with a renal mass with fat attenuation at CT, especially in the presence of calcification (8). It is a rare condition, with fewer than 20 cases having been reported in the literature (2,3,5,(8)(9)(10).…”

“…Renal cell carcinoma with osseous metaplasia is an important entity to consider when confronted with a renal mass with fat attenuation at CT, especially in the presence of calcification (8). It is a rare condition, with fewer than 20 cases having been reported in the literature (2,3,5,(8)(9)(10). The imaging finding of a renal mass with foci of fat attenuation being encased by a peripheral rim of calcification is characteristic of renal cell carcinoma with osseous metaplasia.…”

Renal cell carcinoma with osseous metaplasia: A case report and literature review

“…Osseous metaplasia has also been reported in patients with renal diseases, including less than 20 cases of the major subtypes of RCC [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][23][24][25][26]. Table 1 summarizes clinicopathologic features of these cases, including the present case, reported in case studies of osseous metaplasia associated with RCC.…”

Papillary Renal Cell Carcinoma with Extensive Osseous MetaplasiaA Case Report

“…[6][7][8][9] Only 3 cases reported in world literature which is associated with papillary RCC. [10][11][12] In conclusion, papillary RCC with osseous metaplasia is rare finding, its prognostic significance need to be investigated by large follow up study.…”