A Case of Osteopetrosis (Albers-Schonberg) with Intercurrent Pneumocystis Pneumonitis

Haemolytic Anaemia in Osteopetrosis: A Report of Two Cases

“…Although in Sjolin's cases, erythropoiesis in the spleen was described as being lively, in our patients and in the case described by Aherne (1960) no evidence of increased haemopoiesis was found. It is therefore not invariably the case that the spleen is an important organ of haemopoiesis in osteopetrosis.…”

“…Also, although haemorrhages were present in both cases in the form of purpura with slight epistaxis and there were multiple small haemorrhages in all tissues examined histologically, these could hardly be held responsible for the severe anaemia developing so rapidly after each blood transfusion. It is interesting to note that purpura was present in Case 1, even when the platelet count was normal and it is noteworthy that Aherne (1960) mentioned that in his case the same situation obtained. He described the platelets of his case as being morphologically abnormal, but this feature was not found in our patients.…”