A Case of Pancreatic Pseudocyst with an Atypical Multilocular Appearance on Endoscopic Ultrasound

Park, Jae Hyung; Jung, Min Kyu; Cho, Chang Min; Kim, Gab Chul; Ryeom, Hun Kyu; Kim, Sang Geol; Yoon, Young Kook; Bae, Han Ik

doi:10.5009/gnl.2010.4.2.270

Cited by 1 publication

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“…Despite the recent improvements of many diagnostic tools, current imaging modalities cannot differentiate benign from premalignant or malignant CLPs with sufficient accuracy. 7 In addition, preoperative tissue diagnosis such as cyst aspiration via EUS does not provide a sufficient diagnostic yield. 2 Therefore, knowledge about the long-term natural history of CLPs is essential for establishing the optimal management strategy.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Outcome of Cystic Lesions in the Pancreas: A Retrospective Cohort Study

Ahn¹,

Lee²,

Kim³

et al. 2012

Gut Liver

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Background/AimsThe management guidelines for cystic lesions of the pancreas (CLPs) are not yet well established. This study was performed to document the long-term clinical outcome of CLPs and provide guidelines for the management and surveillance of CLPs.MethodsIn this retrospective cohort study, an additional follow-up was performed in 112 patients with CLPs enrolled from 1998 to 2004 during a previous study.ResultsDuring follow-up for the median period of 72.3 months, the size of the CLPs increased in 18 patients (16.1%). Six of these patients experienced growth of their CLPs after 5 years of follow-up. Twenty-six patients underwent surgery during follow-up, and four malignant cysts were detected. The overall rate of malignant progression during follow-up was 3.6%. The presence of mural nodules or solid components was independently associated with the presence of malignant CLPs. Seven patients underwent surgery after 5 years of follow-up. The pathologic findings revealed malignancies in two patients. There was only one pancreas-related death during follow-up.ConclusionsThe majority of CLPs exhibit indolent behavior and are associated with a favorable prognosis. However, long-term surveillance for more than 5 years should be performed because of the potential for growth and malignant transformation in CLPs.

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Section: Introductionmentioning

confidence: 99%