A case of patent ductus arteriosus in a holstein calf

Lee, Byeong Han; Kim, Won Gon

doi:10.4142/jvs.2004.5.1.83

Cited by 7 publications

(8 citation statements)

References 6 publications

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“…However, it was supposed that CHD may result from injury during development or from single recessive genes or polygenic sets that have lesionspecific effects on cardiac development (Smith, 2009;Jafari Dehkordi et al, 2010). PDA may be accidently found in calves as previously reported during an experiment on an implantable ventricular assist device in Korean calf (Lee and Kim, 2004). In this report we described histopathology of tissues in CHD affected calves and correlated our findings to bacteriological and immunohistochemical parameters.…”

Section: Introductionsupporting

confidence: 57%

Retrospective Studies on Bovine Calves Affected With Congenital Heart Disease

Awadin

2017

Assiut Veterinary Medical Journal

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Congenital heart disease (CHD) was reported in 4 necropsied calves referred to Mansoura veterinary teaching hospital during the period 2014-2016. The Four necropsied calves suffered from patent foramen ovale (PFO) (n=1), high ventricular septal defect (HVSD) (n=2) and persistent ductus arteriosus (PDA) (n=1). VSD was accompanied by valvular hematoma in 1 calf, hydropericardium, right ventricular hypertrophy and dextroposition of the aorta in another calf. Pasteurella multocida (P. multocida) was isolated from one lung lesion associated with VSD. Histopathological examination of different tissues from necropsied CHD affected calves was made. We concluded that extramedullary hematopoiesis in liver and lymphoid organs besides chronic interstitial nephritis were constant findings associated with CHD in calves.

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Section: Introductionsupporting

confidence: 57%

Retrospective Studies on Bovine Calves Affected With Congenital Heart Disease

Awadin

2017

Assiut Veterinary Medical Journal

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“…This condition has been infrequently reported in calves and the genetic background for this abnormality was suggested by Penrith [ 12 , 13 ]. It was postulated that it can affect body growth and result in poor body condition [ 14 ]. An earlier study by West [ 15 ] indicated that the cardiac anomalies, including patent ductus arteriosus, are occasionally related with the abnormalities of kidneys, eyes, and the skeletal system.…”

Section: Discussionmentioning

confidence: 99%

Congenital Malformations in a Holstein-Fresian Calf with a Unique Mosaic Karyotype: A Case Report

Uzar

Szczerbal

Serwańska-Leja

et al. 2020

Animals

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A Holstein-Fresian calf with multiple congenital malformations was subjected postmortem to anatomical and genetic investigation. The calf was small (20 kg), had shortened limbs and was unable to stand up. It lived only 44 days. Detailed anatomical investigation revealed the following features: head asymmetry, the relocation of the frontal sinus and eye orbits, hypoplastic thymus without neck part, ductus Botalli, unfinished obliteration in umbilical arteries, and a bilateral series of tooth germs in the temporal region. Cytogenetic examination, performed on in vitro cultured fibroblasts, showed a unique mosaic karyotype with a marker chromosome—60,XX[9 2%]/60,XX,+mar[8%], which was for the first time described in cattle. No other chromosome abnormalities indicating chromosome instabilities, like chromatid breaks or gaps were identified, thus teratogenic agent exposure during pregnancy was excluded. The marker chromosome (mar) was small and it was not possible to identify its origin, however, sequential DAPI/C (4’,6-diamidino-2-phenylindole) band staining revealed a large block of constitutive heterochromatin, which is characteristic for centromeric regions of bovine autosomes. We suppose that the identified marker chromosome was a result of somatic deletion in an autosome and its presence could be responsible for the observed developmental malformations. In spite of the topographic distance among the affected organs, we expected a relationship between anatomical abnormalities. To the of our best knowledge, this is the first case of a mosaic karyotype with a cell line carrying a small marker chromosome described in a malformed calf.

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“…4 An incidental PDA was found in a 3-month-old Holstein heifer during an experiment evaluating an implantable ventricular assist device. 5 In cattle, the presence of a PDA results in a clinical presentation of increased and prolonged recumbency, ascites, cyanosis, and death. [4][5][6] In older cattle, PDA leads to poor growth rates and body condition.…”

Section: Discussionmentioning

confidence: 99%

“…5 In cattle, the presence of a PDA results in a clinical presentation of increased and prolonged recumbency, ascites, cyanosis, and death. [4][5][6] In older cattle, PDA leads to poor growth rates and body condition. 6 O'Grady et al 7 published a case report in which they described a 4-week old Holstein heifer that was given a diagnosis of a PDA on the basis of results of a 2-dimensional echocardiogram with validation through cardiac catheterization; this was the case study in which cardiac catheterization and angiography in a Holstein heifer for the diagnosis of PDA was used.…”

Section: Discussionmentioning

confidence: 99%

Surgical ligation of patent ductus arteriosus in a dorper sheep

et al. 2018

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Objective: To report the diagnosis and treatment of a companion dorper wether with patent ductus arteriosus (PDA). Study design: Case report. Animal: An 8-month-old dorper wether presented to its primary care veterinarian for a persistent cough and was referred for suspected heart failure on the basis of physical examination and thoracic radiography. A PDA was diagnosed on echocardiography. Methods: The sheep underwent cardiac catheterization and angiogram to measure pulmonary arterial and right ventricular (RV) pressures, identify the morphology of the PDA, and determine whether an intravascular occlusion of the PDA was feasible. Pulmonary artery pressure was 84/53 mm Hg (mean = 66), and RV pressures were 79/5 mm Hg (mean = 45); these were consistent with pulmonary hypertension. The size and shape of the PDA precluded vascular occlusion. Instead, the PDA was ligate through a left fourth intercostal approach. Results: The sheep improved clinically after surgery. The PDA seemed closed on echocardiogram 3 days after surgery. Measurement of postoperative fractional shortening was consistent with decreased left ventricular systolic function that had resolved according to follow-up echocardiography. Conclusion: We report the first known diagnostic evaluation and successful treatment of naturally occurring PDA in a companion sheep. Clinical significance: For economically valuable small ruminants, radiographs, echocardiography and cardiac catheterization can be used to diagnose and plan surgical treatment of PDAs, with a potential for a good long-term outcome.

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A case of patent ductus arteriosus in a holstein calf

Cited by 7 publications

References 6 publications

Retrospective Studies on Bovine Calves Affected With Congenital Heart Disease

Retrospective Studies on Bovine Calves Affected With Congenital Heart Disease

Congenital Malformations in a Holstein-Fresian Calf with a Unique Mosaic Karyotype: A Case Report

Surgical ligation of patent ductus arteriosus in a dorper sheep

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