A case of phaeohyphomycosis of the face caused by Exophiala oligosperma in an immunocompromised host

Sato, Tomotaka; Yaguchi, Takashi

doi:10.1111/ddg.12158

Cited by 7 publications

(2 citation statements)

References 8 publications

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“…In a survey in the USA in 2007, Exophiala dermatitis was the species most frequently isolated, followed by E. xenobiotica, E. lecanii‐corni , Exophiala phaeomuriformis and E. jeanselmei in that order 5 . Recently, E. xenobiotica , 6 E. lecani‐cornii , 7 Exophiala oligospermas 8,9 and E. jeanselmei 10,11 have been reported in Japan as causative agents of phaeohyphomycosis. In our review, we found that since 2009, the proportion of E. jeanselmei has decreased and the number of other species has increased, especially E .…”

Section: Discussionmentioning

confidence: 99%

Subcutaneous phaeohyphomycosis due to Exophiala jeanselmei following renal transplantation: A case report with a published work review of phaeohyphomycosis in Japan

Takenaka

Murota

Nishimoto³

2020

The Journal of Dermatology

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We describe a case of cutaneous phaeohyphomycosis following renal transplantation and include a review of the previously published Japanese cases. A 40‐year‐old Japanese woman taking immunosuppressants following renal transplantation 6 years prior presented to our hospital with a subcutaneous lesion on her right leg. Skin biopsy revealed an abscess, and culture confirmed Exophiala jeanselmei to be the causative agent. Treatment with itraconazole combined with surgical drainage was effective, and the lesion disappeared after 15 months. Upon review of 128 Japanese phaeohyphomycosis cases, it was found that more than 80% of the cases occurred in patients aged more than 60 years, and most cases involved underlying diseases associated with immunodeficiency. E. jeanselmei was the most common etiologic fungus. Recently, however, the Exophiala species has been reclassified based on molecular identification, and cases due to E. jeanselmei decreased with the concomitant increase of cases due to Exophiala oligosperma and Exophiala xenobiotica. In approximately half of the cases, lesions were treated by surgical removal, with or without concomitant antifungal drugs. Itraconazole was the antifungal agent most frequently used. In many cases, the disease course was reported as either healing or improving. There was no difference in either treatment or prognosis based on the etiologic species of fungus.

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Section: Discussionmentioning

confidence: 99%

Subcutaneous phaeohyphomycosis due to Exophiala jeanselmei following renal transplantation: A case report with a published work review of phaeohyphomycosis in Japan

Takenaka

Murota

Nishimoto³

2020

The Journal of Dermatology

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“…Our patient received higher doses of immunosuppressive therapy; which may have been a contributing factor to his earlier development of phaeohyphomycosis in the postoperative period. A summary of previously reported skin infections with E. oligosperma is shown (Table 1) (Bossler et al, 2003;Tokuhisa et al, 2011;Kan et al, 2013;Sato and Yaguchi, 2013;Fukai et al, 2013).…”

Section: Mycologymentioning

confidence: 99%

A Case of Phaeohyphomycosis Caused by Exophiala oligosperma in a Renal Transplant Patient Successfully Treated with Posaconazole

Levy¹,

Rehman²,

Sutton³

et al. 2015

American Journal of Infectious Diseases

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Onychomycosis Associated with Exophiala oligosperma in Taiwan

et al. 2015

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A fungus was isolated from a nail of a 54-year-old female patient with onychomycosis in Taiwan. Based on ITS rDNA as well as beta tubulin gene sequences and microscopic analyses, this fungus was identified as Exophiala oligosperma. This is the first record of E. oligosperma in Taiwan. Negative keratin azure test indicates that keratin degradation is not involved in cases of E. oligosperma associated with skin and nail diseases.

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A case of phaeohyphomycosis of the face caused by Exophiala oligosperma in an immunocompromised host

Cited by 7 publications

References 8 publications

Subcutaneous phaeohyphomycosis due to Exophiala jeanselmei following renal transplantation: A case report with a published work review of phaeohyphomycosis in Japan

Subcutaneous phaeohyphomycosis due to Exophiala jeanselmei following renal transplantation: A case report with a published work review of phaeohyphomycosis in Japan

A Case of Phaeohyphomycosis Caused by Exophiala oligosperma in a Renal Transplant Patient Successfully Treated with Posaconazole

Onychomycosis Associated with Exophiala oligosperma in Taiwan

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