A Case of Premature Hair Graying Treated with Ferrous Sulfate

Choi, Joong-Woon; Lew, Bark‐Lynn; Sim, Woo‐Young

doi:10.5021/ad.2016.28.6.775

Cited by 6 publications

(8 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The pattern of scalp regional graying development did not essentially differ between sexes but more males (75.5%) had hair graying initially involving the parietal areas than in the females whose regional graying patterns were mostly equally distributed all over the scalp regions. behaviors such as smoking and sedentary life style were reported by a huge proportion of participants [8,15,16] whereas some other studies established a weak association or no association at all [17]. The consequential psychological effects to the sufferers were enormous among the participants of the present study.…”

Section: Resultsmentioning

confidence: 45%

Premature Hair Graying: Profiling the Scalp Anatomical Patterns of Occurrence in Tanzania

Russa¹,

Haonga²,

Mboneko³

2017

IJAR

View full text Add to dashboard Cite

Introduction: Premature hair graying (PHG) is a relatively common condition affecting up to 50% of the young people before age 30. Hair graying has adverse effects on self esteem, socio-cultural acceptance and may lead to social stigma and discrimination. Studies have linked PHG with a variety of underlying ill-health conditions such as myocardial infarction, cancer, osteopenia, stroke and cirrhosis. In Tanzania and indeed in Africa at large, PHG is rarely studied. The present study aimed to describe the pattern of onset and anatomical distribution of premature hair graying among the young adult sufferers.

show abstract

Section: Resultsmentioning

confidence: 45%

Premature Hair Graying: Profiling the Scalp Anatomical Patterns of Occurrence in Tanzania

Russa¹,

Haonga²,

Mboneko³

2017

IJAR

View full text Add to dashboard Cite

show abstract

“…Many a times, treatment of concomitant disease is associated with reversal of PGH for example, psoriasis (puvasol), 80 celiac disease, 81 iron therapy for IDA. 18 5 | CONCLUSION the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. "…”

Section: Discussionmentioning

confidence: 99%

“…Coming to mineral deficiency, many mineral deficiency was reported to be associated with PGH for example, Calcium, 36,53,55 copper, 5 Zinc, 5,53 and iron status. 5,18,36,37,53,55 Among mineral deficiencies, significant association was seen between PGH and low serum calcium and ferritin levels (Figure 3). There was exception for the levels of lead and selenium where Kiafar et al 49 showed no significant difference in patients with and without PHG.…”

Section: Vitamin and Mineral Deficienciesmentioning

confidence: 95%

Premature graying of hair: Risk factors, co‐morbid conditions, pharmacotherapy and reversal—A systematic review and meta‐analysis

Mahendiratta

Sarma

Kaur

et al. 2020

Dermatologic Therapy

View full text Add to dashboard Cite

Premature graying of hair (PGH) being a very common entity for which pharmacotherapy and reversibility are not properly addressed. Therefore, this systematic review was conducted to address these issues. For this relevant study were selected from various databases including PubMed, EMBASE, OVID, Web of science, Scopus, and Google Scholar till January 20, 2019. Studies which reported risk factors, co-morbid conditions associated with PGH, its pharmacotherapy and reversal were included in the study. Although many risk factors are reported in literature, smoking, vitamin deficiency (B12, folic acid, and B7), mineral deficiency (low serum calcium and serum ferritin) are found to be associated with PGH. Other important risk factors are family history of PGH, obesity, high B.P, lack of exercise, drugs, genetic syndromes, dyslipidemia, thyroid disorders, hyperuricemia, and alteration in liver function. PGH is found to be an important marker of CAD, more so in case of smoker. Among different pharmacotherapeutic management options, low grade recommendation (2A) is given to calcium pantothenate, PABA, calcium pantothenate + PABA combination. Anu-tailam is the only herbal agent evaluated in clinical research settings. Finally, treating the accompanying pathologies led to the reversal of the disease in many cases. K E Y W O R D S co-morbidities, premature graying of hair, reversal, risk factors, treatment 1 | INTRODUCTION Hair graying is a part of aging, which typically starts around 34.2 ± 9.6 years (whites) to 43.9 ± 10.3 years (in blacks). 1 Premature graying of hair (PGH) is said to occur if hair graying starts before the age of 20 (Caucasians) and 30 years in Africans. 1-4 For Indian people, a cut off range of 25 years is suggested. 1,5 DOPA oxidase positive follicular melanocytes are the primary site of pigment production. Hair color basically depends on the eumelanin Abbreviations: BMD, bone mineral density; BMI, body mass index; CAD, coronary artery disease; DBP, diastolic blood pressure; FBS, fasting blood sugar; OR, odds ratio; PABA, paraamino benzoic acid; PGH, premature graying of hair; RCT, randomized controlled trials; SBP, systolic blood pressure; TERT, telomerase reverse transcriptase. Saniya Mahendiratta and Phulen Sarma have contributed equally to this study and both are considered as first authors.

show abstract

“…In addition to genetic factors, age‐related changes in the cellular response to oxidative stress affect melanogenesis, along with the homeostasis and survival rate of melanocyte stem cells (MSCs) and melanocytes [1‐4]. Evidence that hair follicles show regenerative potential even after the apparent production of white hair fibres [5‐7] suggests the possibility of maintaining pigmented hair over a longer duration by manipulating follicular melanocytes.…”

Section: Introductionmentioning

confidence: 99%

Eriodictyonangustifolium extract, but not Eriodictyon californicum extract, reduces human hair greying

Taguchi

Hata

Kamiya

et al. 2020

Intern J of Cosmetic Sci

View full text Add to dashboard Cite

OBJECTIVE: Yerba Santa (Eriodictyon angustifolium and Eriodictyon californicum) has been used for many years in traditional medicine. However, the effect of Yerba Santa on melanogenesis has not yet been investigated. We aimed to assess the biological effects of Yerba Santa on hair pigmentation. METHODS: Yerba Santa extracts were assessed for their cytological effects following X-ray irradiation treatment and then tested directly for the prevention of human hair greying. Ultra-performance liquid chromatography (UPLC) was utilized to identify the individual extract components. RESULTS: Eriodictyon angustifolium extract significantly increased melanin synthesis in the melanoma cell line through activation of the WNT/MITF/tyrosinase-signalling pathway. In contrast, E. californicum had no effect on melanin synthesis. E. angustifolium extract also demonstrated a protective effect against the damage induced by X-ray irradiation in human keratinocytes. Application of the extracts to subjects who had grey beards demonstrated a reduced number of grey beard hair per year specifically with the E. angustifolium extract. A significant decrease in grey head hair was also observed after application of E. angustifolium extract. Upregulation of gene expression related to melanin production and WNT signalling was observed after the application of E. angustifolium extract. Sterubin was the most abundant flavonoid detected by UPLC in E. angustifolium extract. In addition, sterubin showed the highest difference in terms of quantity, between E. angustifolium and E. californicum extract. CONCLUSION: Eriodictyon angustifolium extract, which is abundant in sterubin, may be suitable as a potential cosmetic and medical agent for the prevention and improvement of hair greying. et E. californicum. CONCLUSION: L'extrait d'E. angustifolium, qui est abondant en st erubine, peut convenir comme agent cosm etique et m edical potentiel pour la pr evention et l'am elioration du grisonnement des cheveux.

show abstract

A Case of Premature Hair Graying Treated with Ferrous Sulfate

Cited by 6 publications

References 4 publications

Premature Hair Graying: Profiling the Scalp Anatomical Patterns of Occurrence in Tanzania

Premature Hair Graying: Profiling the Scalp Anatomical Patterns of Occurrence in Tanzania

Premature graying of hair: Risk factors, co‐morbid conditions, pharmacotherapy and reversal—A systematic review and meta‐analysis

Eriodictyonangustifolium extract, but not Eriodictyon californicum extract, reduces human hair greying

Contact Info

Product

Resources

About