A case of primary disseminated rhinosporidiosis and dapsone-induced autoimmune hemolytic anemia: A therapeutic misadventure

Ghosh, Ritwik; Mondal, Subhargha; Roy, Dipayan; Ray, Alok K.; Mandal, Arpan; Benito‐León, Julián

doi:10.1016/j.idcr.2021.e01076

Cited by 5 publications

(3 citation statements)

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“…Cases of rhinosporidiosis have been described mainly in horses (Argenta et al, 2018;Tizzano et al, 2021;Zibordi et al, 2020), humans (Ghosh et al, 2021;Sarkar et al, 2020;Tiwari et al, 2015), and sporadically in cattle (Riet-Correa et al, 1983), mules (Berrocal & López, 2007), canines (Borrás et al, 2020;Borteiro et al, 2018;Cridge et al, 2021), cats (Brenseke & Saunders, 2010;Moisan & Baker, 2001) and waterfowl (Kennedy et al, 1995). Lesions are characterized by polypoid, granulomatous, friable and painless nodules, which can occur in the nasal cavity, larynx, ocular conjunctiva, skin, oral mucosa, genitalia, lips and ears (Tiwari et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Epidemiological, clinical and anatomopathological characterization of nasal rhinosporidiosis in a horse

Matias

Soares²,

Gurgel³

et al. 2022

RSD

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The objective of this study is to describe the clinical, epidemiological and anatomopathological aspects of a case of nasal rhinosporidiosis in a horse in the Northeast of Brazil. A 15-year-old female horse of mixed breed presented a nodule in the mucosa of the right nasal septum. Surgical excision was performed and sent for histopathological examination. Macroscopically, the nodule had an irregular and reddish surface, and when cut it was soft, whitish, and polypoid in shape. Microscopically, myriads of sporangia with endospores inside were observed in the lamina propria, morphologically similar to Rhinosporidium seeberi in various stages of maturation. The structures were also evidenced and marked by periodic acid Schiff (PAS), Grocott methenamine silver (GMS) and toluidine blue. The diagnosis of rhinosporidiosis was made based on macroscopic aspects and confirmed through histopathological examination. The presence of myriads of sporangia measuring 115 to 220 µm, containing endospores in its interior allowed the diagnosis. Although rhinosporidiosis is considered rare in Brazil, in the Northeast region there are descriptions of the disease in humans, suggesting that the disease in animals occurs and has possibly not been diagnosed. Therefore, it is important to include it as a differential diagnosis of diseases that affect the nasal cavity of horses in the region and that present similar lesions.

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Section: Introductionmentioning

confidence: 99%

Epidemiological, clinical and anatomopathological characterization of nasal rhinosporidiosis in a horse

Matias

Soares²,

Gurgel³

et al. 2022

RSD

View full text Add to dashboard Cite

show abstract

“…Sessile or pedunculated polyps affecting nose and nasopharynx is the most common presentation. There are predominantly three modes of cutaneous transmission;[ 1 ] autoinoculation, hematogenous transmission, and direct implantation. Cutaneous dissemination has been reported to occur in immunocompetent[ 2 ] as well as immunosuppressed[ 3 ] patients.…”

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confidence: 99%

“…[ 4 ] and Ghosh et al . [ 1 ] Cutaneous rhinosporidiosis has protean manifestations. Literature review shows tumor like nodules, warty papules and plaques, subcutaneous nodules and giant masses resembling soft tissue tumors to be the most common presentation.…”

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confidence: 99%