A case of primary squamous cell carcinoma of the gallbladder with local invasion of the liver and peritoneum, and metastasis to the omentum

Levy, Anna; Casalduc-Coca, Francisco; Asiry, Saeed; Goodman, Allen C.

doi:10.1016/j.radcr.2017.09.026

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Patients are usually asymptomatic or have vague presenting symptoms like anorexia, abdominal pain, nausea, and vomiting and in case of advanced disease, there will be weight loss, obstructive jaundice, ascites, palpable abdominal mass, and hepatomegaly [3] . Rarely, SCC may present as liver abscess probably due to direct involvement of liver parenchyma and associated necrosis [4] .…”

Section: Introductionmentioning

confidence: 99%

Squamous cell carcinoma of the gallbladder masquerading liver abscess with review of literature

Jena

Meher

2022

International Journal of Surgery Case Reports

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Introduction and importance Squamous cell carcinoma of the gall bladder is a rare but aggressive tumor. It has a wide variety of presentations. Presentation as a liver abscess is a rare condition only 2 cases reported in the literature before. Case report A 45-year-old male patient presented to the emergency with complaints of fever, right upper quadrant pain, and jaundice. On evaluation, an initial diagnosis of the liver abscess was made. Due to the deteriorating condition of the patient, he was taken up for surgery. Upon exploration, there were multiple deposits over the bilateral lobes of the liver, so a controlled drainage of abscess cavity was done with biopsy from the wall of the gall bladder and liver metastasis was taken which showed squamous cell carcinoma of gall bladder with liver metastasis. The patient was given gemcitabine and oxaliplatin as palliative chemotherapy. He died after 11 months of presentation. Discussion and conclusion The aggressive and advanced nature of the disease at the presentation poses a formidable challenge in managing such patients but early diagnosis and surgical management can provide long term benefits.

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Section: Introductionmentioning

confidence: 99%

Squamous cell carcinoma of the gallbladder masquerading liver abscess with review of literature

Jena

Meher

2022

International Journal of Surgery Case Reports

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Primary Squamous Cell Carcinoma of the Gallbladder: Case Report

Dashti,

Garousi,

Mirzaee

et al. 2024

Clinical Case Reports

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Pure gallbladder squamous cell carcinoma is rare. Adenocarcinoma is the foremost malignant pathology of gallbladder cancer. Simultaneously, squamous cell carcinoma accounts for only 1% of malignant gallbladder tumors. They are often advanced at diagnosis and associated with a poor prognosis. The patient was a 37‐year‐old man diagnosed with poorly differentiated squamous cell carcinoma of the gallbladder. Cholecystectomy, right hemicolectomy, hepatic wedge resection, and regional lymph node dissection were performed, and then he received six courses of adjuvant chemotherapy with the FOLFOX regimen. After 2 months, liver metastasis was diagnosed, and a chemotherapy regimen consisting of gemcitabine, cisplatin, and pembrolizumab was started. After three courses, stable disease was seen. Surgery is the main treatment. There is no consensus about the best adjuvant treatment. The results obtained from this patient might help elucidate the role of adjuvant therapies in treating this rare case report.

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A case of primary squamous cell carcinoma of the gallbladder with local invasion of the liver and peritoneum, and metastasis to the omentum

Cited by 2 publications

References 11 publications

Squamous cell carcinoma of the gallbladder masquerading liver abscess with review of literature

Squamous cell carcinoma of the gallbladder masquerading liver abscess with review of literature

Primary Squamous Cell Carcinoma of the Gallbladder: Case Report

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