A case of pseudotumor cerebri following glucocorticoid therapy in which warfarin prevented recurrence.

Abstract

A patient with nephrotic syndrome developed pseudotumor cerebri following glucocorticoid therapy. Diagnosis of pseudotumor cerebri was based on satisfaction of four criteria proposed by Ahlskog and O'Neill. The symptomsof pseudotumor cerebri disappeared within 10 days. After a three-week interval of remission, relapse occurred. Glycerol and urokinase produced rapid resolution of the symptomsand warfarin prevented further recurrence of pseudotumor cerebri for one year. These results suggest that the pathogenesis of pseudotumor cerebri might be associated with the hypercoagulable state which was induced by glucocorticoid therapy and nephrotic syndrome.

Ophthalmic features of idiopathic intracranial hypertension

“…In the past 10 years, no more than 60 cases of IIH were documented in Asian countries and most of them were sporadic case reports. [5][6][7][8][9][10][11][12] With such few case numbers, the true incidence in Oriental people remained unknown.…”

Letters to the Editor

“…Most recurrences are single events and occur within after an interval of 0.8–4 years 8,9 . An adult male is described who developed PC in nephrotic syndrome following glucocorticoid therapy 10 . The symptoms of PC disappeared within 10 days.…”