A Case of Pulmonary Hyalinizing Granuloma Associated with Posterior Uveitis

Eşme, Hıdır; Ermiş, Sıtkı Samet; Fidan, Fatma; Ünlü, Mehmet; Dılek, Fatma Hüsniye

doi:10.1620/tjem.204.93

Cited by 22 publications

(18 citation statements)

References 10 publications

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“…More than half of the patients have autoimmune phenomena or previous exposures to mycobacterial or fungal antigens [3]. It was first described in literature by Engleman, et al in 1977.…”

Section: Discussionmentioning

confidence: 99%

“…It has been usually reported as case reports in the literature. It's frequently seen in the 4 th -5 th decades, and the male/female ratio is approximately equal [1][2][3][4].…”

Section: Discussionmentioning

confidence: 99%

“…The radiological appearance of the lesion is that of multiple, bilateral nodules which sometimes mimic metastatic carcinoma [1][2][3]. Although the etiopathogenesis of PHG is unknown, it has been postulated that it represents an exaggerated immune response, possibly due to chronic granulomatous infections such as tuberculosis or histoplasmosis or antigen-antibody complexes so that this immune response may result in deposition of immunoglobulins or immune complexes in the lung [1][2][3][4][5][6][7][8]. A patient with suspected lung cancer was diagnosed pulmonary hyalinizing granuloma by transthoracic fine needle aspiration (TTFNA).…”

Section: Introductionmentioning

confidence: 99%

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Pulmonary Hyalinizing Granuloma in the Differential Diagnosis of Pulmonary Carcinoma

Üzer¹,

Hicran²,

Özbudak³

et al. 2018

Clin Med Rev Case Rep

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Pulmonary hyalinizing granuloma (PHG) which should be considered in the differential diagnosis of pulmonary nodules of unknown origin is a distinct fibrosing lesion of lung that occurs in middle-aged patients. It has been usually reported as case reports in the literature. Patients are usually symptomatic. We present the case which recognized during operation and determined rarely. Keywords Bronchoscopy, Pulmonary hyalinizing granuloma, Lung cancer CaseA 62-year-old female presented to the clinic with complaints of dyspnea, cough and sputum. In her history; she had cholecystectomy, hypertension and biomass exposure. Family history was unremarkable. On physical examination, blood pressure 125/75, pulse 95 and fingertip saturation was 97%. Other system examinations were normal. Laboratory examination revealed

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“…More than half of the patients have autoimmune phenomena or previous exposures to mycobacterial or fungal antigens [3]. It was first described in literature by Engleman, et al in 1977.…”

Section: Discussionmentioning

confidence: 99%

“…It has been usually reported as case reports in the literature. It's frequently seen in the 4 th -5 th decades, and the male/female ratio is approximately equal [1][2][3][4].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pulmonary Hyalinizing Granuloma in the Differential Diagnosis of Pulmonary Carcinoma

Üzer¹,

Hicran²,

Özbudak³

et al. 2018

Clin Med Rev Case Rep

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“…4,5) It has been proposed that the nodule may represent an abnormal immune response to infectious agents or an autoimmune process, since many immunemediated diseases appear in association with PHG. 6,7) Case reports of PHG have described associations with prior tuberculosis, histoplasmosis and pulmonary fungal infections. 1,2,6) Patients with PHG have been found to have a number of autoimmune abnormalities, including antinuclear antibodies, rheumatoid factor, and antismooth-muscle, anti-microsomal and anti-thyroglobulin antibodies.…”

Section: Discussionmentioning

confidence: 99%

“…6,7) Case reports of PHG have described associations with prior tuberculosis, histoplasmosis and pulmonary fungal infections. 1,2,6) Patients with PHG have been found to have a number of autoimmune abnormalities, including antinuclear antibodies, rheumatoid factor, and antismooth-muscle, anti-microsomal and anti-thyroglobulin antibodies. Case reports have described associations with autoimmune conditions such as rheumatoid arthritis, multiple sclerosis, uveitis, Castleman's disease, sclerosing mediastinitis and retroperitoneal fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Hyalinizing Granuloma Detected in a Family Member after Confirmation of Tuberculosis in His Father

Matsuoka

Imanishi

Matsuoka

et al. 2014

ATCS

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Pulmonary hyalinizing granuloma (PHG) is an uncommon lung disease that usually presents as bilateral multiple nodules, and more rarely as a solitary nodule. An exaggerated immune response to antigenic stimuli resulting from infection or an autoimmune process has been suggested as the cause of PHG. Here, we describe a rare case of solitary PHG that was detected in a family member after tuberculosis had been confirmed in his father, without any background of infectious disease or autoimmune abnormality.

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Pulmonary hyalinizing granuloma and retroperitoneal fibrosis in an adolescent

et al. 2006

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We describe a 15-year-old boy who developed pulmonary hyalinizing granuloma (PHG) and retroperitoneal fibrosis (RPF). His PHG and RPF were not associated with histoplasmosis or tuberculosis and appeared to represent idiopathic autoimmune phenomena. This is the first reported case of PHG in a pediatric patient and the fourth reported co-occurrence of PHG and RPF. The use of F-18 fluorodeoxyglucose positron emission tomography in the diagnostic and follow-up evaluation of PHG is reported.

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A Case of Pulmonary Hyalinizing Granuloma Associated with Posterior Uveitis

Cited by 22 publications

References 10 publications

Pulmonary Hyalinizing Granuloma in the Differential Diagnosis of Pulmonary Carcinoma

Pulmonary Hyalinizing Granuloma in the Differential Diagnosis of Pulmonary Carcinoma

Pulmonary Hyalinizing Granuloma Detected in a Family Member after Confirmation of Tuberculosis in His Father

Pulmonary hyalinizing granuloma and retroperitoneal fibrosis in an adolescent

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