2021
DOI: 10.1007/s00011-021-01491-w
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A case of reactivation of varicella–zoster virus after BNT162b2 vaccine second dose?

Abstract: We report a case of itchy papulovesicular rash consistent with varicella–zoster virus reactivation after Pfizer-BioNTech vaccine second dose administration. While there have been cases of varicella–zoster virus reactivation due to COVID-19 or COVID-19 vaccine inoculation in older individuals with pre-existing conditions, this case report describes the first case of varicella–zoster virus reactivation on a healthy, young male in the absence of pre-existing conditions. The mechanisms underlying varicella-zoster … Show more

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Cited by 21 publications
(19 citation statements)
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“…There have been 12 reports of VZV or HSV reactivation after vaccination [ 1 , 2 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 ]. Fathy et al published a series of 40 cases of VZV ( n = 35) or HSV reactivation ( n = 5) after BNT162b2 or mRNA-1273 vaccination [ 30 ].…”
Section: Resultsmentioning
confidence: 99%
“…There have been 12 reports of VZV or HSV reactivation after vaccination [ 1 , 2 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 ]. Fathy et al published a series of 40 cases of VZV ( n = 35) or HSV reactivation ( n = 5) after BNT162b2 or mRNA-1273 vaccination [ 30 ].…”
Section: Resultsmentioning
confidence: 99%
“…A total of 314 studies were identified. After applying the inclusion and exclusion criteria, 55 studies [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] of VZV manifestations in subjects with SARS-CoV-2 vaccinations or COVID-19 disease were deemed eligible for inclusion. A flow diagram of the selection of the studies is presented in Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Clinically, BCG inflammation presented as a painful, erythematous, and indurated plaque at the BCG scar site [73]. Several cases of herpes simplex virus (HSV) and varicella zoster virus (VZV) reactivation have been documented [6,7,[74][75][76][77]. In a large study of 405 cutaneous reactions, VZV and HSV reactivations were 10% and 3% of the cases, respectively.…”
Section: Flare Of Existing Dermatosesmentioning
confidence: 99%