A Case of Relapsing Polychyondritis that Colchicine was Effective for Improvement of Inflammation

Abstract

Relapsing polychyondritis (RP) is a comparatively rare systemic diseases that is manifested by relapses of painful inflammation to the cartilage tissue of the whole body, especially pinna, the nose and the trachea. It is suspected to be an autoimmune disease because various autologous such as type 2 collagen are admitted although details of the etiology are uncertain.We report a case of 26-year-old woman who had severe subglottic stenosis due to relapsing polychondritis. The stenosis was getting so severe that we had to perform a tracheostomy. At the time of inflammation exacerbation, we had to increase the steroid dosage. It was considered that we should be able to reduce the increase in steroid dosage by treating the RP with colchine.