A Case of Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus Diagnosed during Pregnancy

Katayama, Hiromichi; Ito, Akihiro; Kakoi, Narihiko; Shimada, Shuichi; Saitō, Hideo; Arai, Yoichi

doi:10.1159/000354351

Cited by 6 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Five cases were reported with metastatic disease during pregnancy [18] , [28] , and the remaining were diagnosed with less advanced disease, usually during the second and third trimesters of pregnancy, and few cases were reported during the first trimester [24] , [27] .…”

Section: Clinical Picture and Tumor Characteristicsmentioning

confidence: 99%

Review on renal cell carcinoma and pregnancy: A challenging situation

Khaled

Lahloubi

Rashad³

2016

Journal of Advanced Research

View full text Add to dashboard Cite

show abstract

Section: Clinical Picture and Tumor Characteristicsmentioning

confidence: 99%

Review on renal cell carcinoma and pregnancy: A challenging situation

Khaled

Lahloubi

Rashad³

2016

Journal of Advanced Research

View full text Add to dashboard Cite

show abstract

“…At the present date, there exists only one other report of RCC with IVC tumor thrombus diagnosed during pregnancy. 6 In this report, the tumor thrombus extended only to the level of the infrahepatic IVC (level II tumor thrombus). We present the case of an RCC with IVC tumor thrombus extending into the right atrium (level IV) diagnosed at 24 weeks of pregnancy.…”

Section: Introductionmentioning

confidence: 63%

Renal cell carcinoma with inferior vena cava thrombus extending to the right atrium diagnosed during pregnancy

Simons

Cavallo

Levin

et al. 2017

Therapeutic Advances in Urology

View full text Add to dashboard Cite

Only one case of renal cell carcinoma (RCC) with inferior vena cava (IVC) tumor thrombus diagnosed and treated during pregnancy has been reported in the literature. In that report, the tumor thrombus extended to the infrahepatic IVC (level II tumor thrombus). In the present case, a 37-year-old woman with lupus anticoagulant antibodies was diagnosed with RCC and IVC tumor thrombus extending to the right atrium (level IV tumor thrombus) at 24 weeks of pregnancy. The fetus was safely delivered by cesarean section at 30 weeks of gestation. At 4 days later, an open right radical nephrectomy and IVC and right atrial thrombectomy were performed on cardiopulmonary bypass (CPB) once the patient's hemodynamic status had been optimized. Fetal and maternal concerns included the risk of a thromboembolic event (due to increased hypercoagulability from pregnancy, active malignancy, and lupus anticoagulant), intraoperative hemorrhage risk (due to extensive venous collaterals and anticoagulation), and fetal morbidity and mortality (due to fetal lung immaturity). Standardized guidelines for treatment of RCC with or without IVC tumor thrombus during pregnancy are unavailable due to the infrequency of such cases. Treatment decisions are therefore individualized and this case report may inform the management of future patients diagnosed with RCC with level IV tumor thrombus during pregnancy.

show abstract

“…The extension of renal cell carcinomas into the IVC is relatively rare, but it has been reported even in pregnancy [12] . Nevertheless, the surgery of renal tumors with IVC thrombi is quite complex.…”

Section: Discussionmentioning

confidence: 99%

Surgical Management and Outcome of Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus

Bérczi

Flaskó

Szerafin³

et al. 2017

Urol Int

View full text Add to dashboard Cite

Introduction: The authors of this paper assessed the surgical management and outcome of renal cancers when tumor thrombus extended into the inferior vena cava (IVC). Methods: From 2000 to 2015, 46 radical nephrectomies were performed on patients with tumor thrombus in the IVC. The mean age of the patients was 60 ± 11 years. Radical nephrectomy and thrombectomies were performed in a single session. There were 18 level-IV, 23 level-III, and 5 level-II tumor thrombi. The operations were performed using cardiopulmonary bypass in 14 patients, while deep hypothermic cardiac arrest was carried out in 4 cases. Results: The mean size of the tumors was 9.4 ± 3.5 cm. Histology showed the tumor stages to be pT3b in 21cases, pT3c in 22, and pT4 in 3 patients. The mean follow-up period of the patients was 3.6 ± 3.0 years. During the follow-up period, local recurrence was observed in 7 patients, while distant metastases occurred in 8 cases. The median time to progression was 37 ± 27 months. The 5-year overall survival was 43.7%. Conclusions: Radical nephrectomy and thrombectomy provided reasonable long-term survival for patients with renal cancer and IVC thrombus. However, tumor progression was detected in 41.6%. The presence of tumor thrombus had a negative effect on tumor progression and survival.

show abstract

A Case of Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus Diagnosed during Pregnancy

Cited by 6 publications

References 9 publications

Review on renal cell carcinoma and pregnancy: A challenging situation

Review on renal cell carcinoma and pregnancy: A challenging situation

Renal cell carcinoma with inferior vena cava thrombus extending to the right atrium diagnosed during pregnancy

Surgical Management and Outcome of Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus

Contact Info

Product

Resources

About