A Case of Renal Metastasis of Uterine Leiomyosarcoma

Bajic, Petar; Gange, William S.; Blackwell, Robert H.; Shah, Arpeet; Biemer, John; Picken, Maria M.; Gorbonos, Alex

doi:10.7759/cureus.1470

Cited by 2 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Compared with other urinary malignancies, primary renal leiomyosarcoma has a poor prognosis. Complete resection of the tumor is positively correlated with overall survival, and radical resection is the preferred option for patients (3). There is no difference in survival between advanced renal LMS patients receiving chemotherapy and those who do not receive chemotherapy (4).…”

Section: Discussionmentioning

confidence: 99%

Treatment of renal leiomyosarcoma with right atrial tumor embolus without cardiopulmonary bypass: a case report

Duan,

Bi,

Zhang

et al. 2024

Front. Oncol.

View full text Add to dashboard Cite

ObjectiveTo investigate the clinical manifestations, imaging and pathological features, treatment methods and prognosis of primary leiomyosarcoma of kidney, and the choice of treatment with tumor thrombus.MethodsThe clinical data of a patient with primary renal leiomyosarcoma complicated with inferior vena cava and right atrial tumor thrombus were retrospectively analyzed. Radical resection of right kidney without cardiopulmonary bypass and removal of inferior vena cava and right atrial tumor thrombus were performed. Adjuvant intravenous chemotherapy was given according to the results, and follow-up observation was made.ResultsPostoperative pathological findings were: leiomyosarcoma (right renal tumor), the size of the mass was about 12.1 cm, and no cancer was found at the incision end of the right ureter.ConclusionPrimary leiomyosarcoma of kidney is rare in clinical practice, and complication of right atrial tumor embolus is even rarer. The disease has high malignant degree and poor prognosis. The clinical manifestations and imaging examinations were non-specific, and pathological diagnosis was the gold standard. Radical surgical resection is the main treatment method at present, and it provides experience for the treatment of grade IV tumor thrombus without cardiopulmonary bypass.

show abstract

Section: Discussionmentioning

confidence: 99%

Treatment of renal leiomyosarcoma with right atrial tumor embolus without cardiopulmonary bypass: a case report

Duan,

Bi,

Zhang

et al. 2024

Front. Oncol.

View full text Add to dashboard Cite

show abstract

“…Renal involvement by cervical carcinoma in the clinical setting is rare. [110][111][112] Some cases of renal metastases from uterine serous carcinoma, 113 endometrial adenocarcinoma, 114,115 uterine leiomyosarcoma, 116 and ovarian granulosa cell tumor 117 have also been reported.…”

Section: Gynecologicmentioning

confidence: 99%

Secondary Tumors of the Kidney: A Comprehensive Clinicopathologic Analysis

Saeed

Osunkoya²

2022

Advances in Anatomic Pathology

View full text Add to dashboard Cite

Metastases to the kidney are rare and were historically described in autopsy series, and the incidence ranged between 2.36% and 12.6%. However, in the contemporary literature with the improvements in imaging modalities (computed tomography scan and magnetic resonance imaging) and other health care screening services, metastatic tumors to the kidney are being diagnosed more frequently in surgical specimens. The utility of needle core biopsies in the primary evaluation of renal masses has also increased the number of sampled metastases, and as a result, only limited histologic material is available for evaluation in some cases and may potentially lead to diagnostic pitfalls. In the last decade, a few large clinical series have been published. In these series, the majority of metastatic tumors to the kidney are carcinomas, with the lung being the most common primary site. A significant number of the various tumor types with metastasis to the kidney are also associated with widespread metastases to other organs, and the renal metastasis may present several years after diagnosis of the primary tumor. The majority of secondary tumors of the kidney are asymptomatic, incidentally discovered, and solitary. There should be a high index of suspicion of metastasis to the kidney in patients with an associated enlarging renal lesion with minimal to no enhancement on imaging and tumor progression of a known high-grade nonrenal malignancy. Secondary tumors of the kidney can be accurately diagnosed by correlating histopathologic features with clinical and radiographic findings and the judicious use of ancillary studies.

show abstract

A Case of Renal Metastasis of Uterine Leiomyosarcoma

Cited by 2 publications

References 8 publications

Treatment of renal leiomyosarcoma with right atrial tumor embolus without cardiopulmonary bypass: a case report

Treatment of renal leiomyosarcoma with right atrial tumor embolus without cardiopulmonary bypass: a case report

Secondary Tumors of the Kidney: A Comprehensive Clinicopathologic Analysis

Contact Info

Product

Resources

About