A case of renal tuberculosis following BCG therapy for bladder cancer

Asymptomatic renal granuloma diagnosed 3 years after Bacillus Calmette–Guérin intravesical injection: A case report and a literature review

“…Renal granuloma is an extremely rare condition that develops in 0.1% of BCG‐treated bladder cancer cases 2 . The patients may present with various associated symptoms, including low‐grade fever, chills, night sweats, flank pain, vomiting, and pain on urination 2–9 . However, our patient remained asymptomatic during and after the course of the intravesical BCG immunotherapy.…”

“…An overview of published reports of renal granuloma related to BCG is described in Table 1. When a definitive diagnosis is made by needle biopsy, patients had typically undergone antituberculotic therapy for at least 3 months and up to 1 year 1,3,4,6–9,11–14 . All patients were responsive to antituberculotic therapy, showing complete cure of renal granuloma and accompanying symptoms 11 .…”

“…When a definitive diagnosis is made by needle biopsy, patients had typically undergone antituberculotic therapy for at least 3 months and up to 1 year. 1,3,4,[6][7][8][9][11][12][13][14] All patients were responsive to antituberculotic therapy, showing complete cure of renal granuloma and accompanying symptoms. 11 However, conservative management was also successful in asymptomatic cases with non-expansile renal lesions.…”

“…2 The patients may present with various associated symptoms, including low-grade fever, chills, night sweats, flank pain, vomiting, and pain on urination. [2][3][4][5][6][7][8][9] However, our patient remained asymptomatic during and after the course of the intravesical BCG immunotherapy. There were no symptoms suggestive of pyelonephritis, such as fever or back pain.…”