A case of retroperitoneal liposarcoma in pregnancy: Case Report

Jaco, P. De; Giorgio, Mario; Zantedeschi, Bruna; Mazzoleni, Guido; Marabini, A

doi:10.3109/00016349309023425

Cited by 11 publications

(11 citation statements)

References 4 publications

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“…However, liposarcoma rarely coexists with pregnancy. Table 1 demonstrates sarcoma diagnosed during pregnancy in the English literature (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) . Rather than first having a tumor diagnosed during pregnancy, our patient had had a retroperitoneal myxoid liposarcoma surgically removed 2 years earlier and was found to have a recurrence during early pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…It is usually locally invasive and may recur following incomplete removal. The surgical resectability and pathologic grade of the tumor are among the strongest predictors of survival (17,19) . Retroperitoneal masses may produce a wide range of symptoms and signs.…”

Section: Discussionmentioning

confidence: 99%

“…Initially, the disease is usually asymptomatic because the retroperitoneal space is easily distended by the enlarging tumor. Later, when compression and infiltration of the surrounding organs develop, there may be localized pain associated with neurologic symptoms because of neuroplexus involvement, vomiting due to gastric compression, gastric hemorrhage because of neoplastic infiltration or secondary portal hypertension, constipation, diarrhea, tenesmus or painful defecation due to bowel involvement, hydronephrosis, pyelonephritis, or obstructive nephropathy due to kidney and ureter compression (17) . The most reliable diagnostic tools are CT and magnetic resonance imaging (19) , which can correctly locate the retroperitoneal tumor and evaluate involvement of the surrounding organs.…”

Section: Discussionmentioning

confidence: 99%

“…The treatment of choice is radical surgery (21,22) . Postoperative radiotherapy is advised if the mass has not been completely resected (17) .…”

Section: Discussionmentioning

confidence: 99%

“…1967 10 S and/or RT NE Not stated Wolfe et al (6) 1969 1 S Not stated TAB Kececioglu (7) 1972 1 S and RT NE TAB Pratt et al (8) 1977 4 S 3 died of mets present at DX; one cured after delivery by surgery 1, TAB; 3, normal Jafari et al (9) 1978 4 None 3 died of mets present at DX; one cured after delivery by surgery Normal Foruhan (10) 1979 2 S and CT NE Normal Blight and Puls (11) 1981 1 S, RT, and CT Died of mets 5 months later Normal Greenberg et al (12) 1982 1 RT and CT Died of mets 7 weeks later Normal Gililland and Weinstein (13) 1983 1 RT and CT Alive 2 years later without mets Normal Simon et al (14) 1984 17 S NE; 12 alive and well; 5 died of mets after delivery 13, normal; 3, TAB; 1: died of RDS Loguidice (15) 1986 1 CT, RT, and S Alive 17 months later without mets Normal Kyodo et al (16) 1989 1 S NE Normal De Jaco et al (17) 1993 1 S Died of disease 8 months later Normal Matsuda et al (18) 2000 2 RT and S Alive 4 years later without mets Normal S, surgery; RT, radiation therapy; CT, chemotherapy; SAB, spontaneous abortion; TAB, therapeutic abortion; RDS, respiratory distress syndrome; NE, no effect on anticipated course of sarcoma; mets, metastases; DX, diagnosis.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Recurrent retroperitoneal myxoid liposarcoma during pregnancy: a case report and literature review

Jeng¹,

Tzen²,

Huang³

et al. 2005

Int J Gynecol Cancer

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Retroperitoneal liposarcoma in pregnancy is rare, and only a few cases of primary liposarcoma during pregnancy have been reported. To the best of our knowledge, there is no published report of retroperitoneal liposarcoma that was previously treated and recurred during pregnancy. Our patient was diagnosed with a pelvic mass on ultrasound at 12-weeks' gestation. The mass was found to be a retroperitonal, well-differentiated myxoid liposarcoma and was radically excised at the time of cesarean delivery at 36-weeks' gestation. However, the tumor recurred soon and progressed rapidly, and the patient eventually died of the disease. A thorough sonographic investigation and timing of surgery may be critical in terms of finding a surgically resectable lesion and leading to a more favorable prognosis.

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