A case of rupioid syphilis

Krase, Ifat Zerin; Cavanaugh, Kevin; Curiel‐Lewandrowski, Clara

doi:10.1016/j.jdcr.2016.01.006

Cited by 11 publications

(8 citation statements)

References 8 publications

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“…Lesions are usually multiple, irregularly distributed on the scalp, face, trunk, and extremities [ 16 , 17 ]. A rapid manifestation, characterised by large papules and plaques covered by a dark crust, has rarely been described too [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Secondary Syphilis Presenting As Palmoplantar Psoriasis

Gianfaldoni¹,

Tchernev²,

Wollina³

et al. 2017

Open Access Maced J Med Sci

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Section: Discussionmentioning

confidence: 99%

Secondary Syphilis Presenting As Palmoplantar Psoriasis

Gianfaldoni¹,

Tchernev²,

Wollina³

et al. 2017

Open Access Maced J Med Sci

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“…In the traditional algorithm, nontreponemal titers (i.e., RPR, VRDL) are tested first. Subsequent confirmatory treponemal testing is then done (i.e., TP‐PA assay, EIAs, CIAs) 16,61 . However, it is important to be aware that HIV patients may have higher rates of false‐negative nontreponemal titers because of the prozone effect 16 .…”

Section: Clinical Featuresmentioning

confidence: 99%

“…Subsequent confirmatory treponemal testing is then done (i.e., TP-PA assay, EIAs, CIAs). 16,61 However, it is important to be aware that HIV patients may have higher rates of false-negative nontreponemal titers because of the prozone effect. 16 If the nontreponemal testing is negative and suspicion for infection is high, treponemal testing should still be done.…”

Section: Diagnosis Is Most Commonly Made With Serological Testsmentioning

confidence: 99%

Malignant syphilis: a new and revised definition

Karanfilian

Almohssen²,

Kapila

et al. 2022

Int J Dermatology

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Malignant syphilis is a rare, severe variant of secondary syphilis that primarily affects immunocompromised patients. Historically, the clinical presentation included a prodrome of constitutional symptoms followed by the development of characteristic skin lesions. The definition of malignant syphilis has not been updated since it was first described as only a cutaneous manifestation. In recent years, syphilis has reemerged as a major public health issue, particularly in men who have sex with men (MSM) and patients with HIV. With increasing rates of syphilis in the HIV‐positive population, the systemic manifestations of malignant syphilis have become more apparent. We propose a revised definition and elucidate why the term malignant syphilis should be expanded to include systemic manifestations, stressing musculoskeletal, central nervous system, ocular, ear, cardiovascular, rectal, liver, lung, and renal involvement. This updated definition is dramatically expanded to reflect its systemic manifestations. Recognition of these manifestations may prevent devastating long‐term effects.

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“…This patient's rapid plasma reagin was reactive with a titer of 1:512, and his Treponema pallidum hemagglutination assay was positive. Rupioid syphilis is characterized by well-demarcated hyperkeratotic scaly plaques with a thick, adherent crust that resembles the back of an oyster shell 1 Hypertrophic lichen planus – Incorrect.…”

Section: Historymentioning

confidence: 99%