A Case of Solitary Neurofibroma in Outer Surface of Nose

AbdollahiFakhim, Shahin; Rezaeian, Saman; Hosseinpour-Feizi, Hojjat; Naghavi-Behzad, Mohammad; Piri, Reza

doi:10.15171/jarcm.2016.039

J Anal Res Clin Med

2016

DOI: 10.15171/jarcm.2016.039

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A Case of Solitary Neurofibroma in Outer Surface of Nose

Shahin AbdollahiFakhim¹,

Saman Rezaeian²,

Hojjat Hosseinpour-Feizi³

et al.

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Cited by 3 publications

References 15 publications

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Diagnostic and treatment challenges in neurofibroma concerning the external nose

Shakrawal¹,

Chouhan²,

Solanki³

2021

J. Laryngol. Otol.

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Background This paper discusses clinical features and management aspects of an extremely rare entity, neurofibroma of the external nose. Methods Database searches were performed using PubMed, Embase and Google Scholar to identify previously published articles. Results Twelve articles comprising 13 patients with neurofibroma of the external nose were included. The mean age of presentation was 31 years. Sixty-nine per cent of patients were diagnosed at final histopathology. External approach rhinoplasty was performed in 76.9 per cent of patients, while the intranasal approach was used in 15.3 per cent of patients. There was a 15.3 per cent association with neurofibromatosis type 1. Recurrence was noted in 23 per cent of patients. Conclusion It may be challenging to diagnose this entity clinically because of its rarity and striking features on histopathology. Neurofibroma of the external nose should be kept in mind as a differential diagnosis for any soft progressive swelling over the nose. Management requires complete excision, with cosmesis and restoration of functions.

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Diagnostic and treatment challenges in neurofibroma concerning the external nose

Shakrawal¹,

Chouhan²,

Solanki³

2021

J. Laryngol. Otol.

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Single Stage Nasal Reconstruction for Solitary Neurofibroma Isolated in the Columella

et al. 2023

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Neurofibromas are benign peripheral nerve sheath tumors that can originate from several elements of peripheral nerves, including axons, Schwann cells, endoneurial fibroblasts, and perineurial cells. The occurrence of a solitary neurofibroma in the external nose, especially that isolated in the nasal columella, is extremely rare. To the best of our knowledge, only 4 cases of solitary neurofibromas in the external nose have been reported in the English literature: on the nasal dorsum, tip, and pyriform aperture, all originating from the trigeminal nerve. We report the first case of a solitary neurofibroma isolated in the nasal columella, which we found in an otherwise healthy 42-year-old man. We completely resected this tumor with a negative resection margin and performed reconstruction with a bilateral spreader graft and caudal septal extension graft using autologous septal cartilage. The postoperative course was successful in both cosmetic and functional results, with no sensory changes at the 1-year follow-up. Surgical treatment for this lesion was challenging due to the cosmetically obvious location and high rate of recurrence. A review of the literature highlights the clinical and histological characteristics, differential diagnosis, and management of solitary neurofibroma of the external nose.

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What is your diagnosis?

Sönmez Ergün,

Kirazoğlu

2024

TURKDERM

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A Case of Solitary Neurofibroma in Outer Surface of Nose

Cited by 3 publications

References 15 publications

Diagnostic and treatment challenges in neurofibroma concerning the external nose

Diagnostic and treatment challenges in neurofibroma concerning the external nose

Single Stage Nasal Reconstruction for Solitary Neurofibroma Isolated in the Columella

What is your diagnosis?

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