A Case of Successful Surgery for Splenic Sarcoidosis With Giant Splenomegaly and Hypersplenism

Nishioka, Hiroaki; Hirabayashi, Kuniaki; Hazano, Koji; Yamaguchi, Takuya; Toguchi, Keisuke; Nakabayashi, Hiroshi

doi:10.3919/jjsa.66.1739

Cited by 5 publications

(1 citation statement)

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“…To the best of our knowledge, only 23 cases of sarcoidosis in chronic dialysis patients have been reported (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24). Their clinical characteristics, laboratory data, and treatment are listed in Table 2.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis in a Chronic Dialysis Patient Diagnosed by Sarcoidosis-related Hypercalcemia with No Common Systemic Clinical Manifestations: A Case Report and Review of the Literature

et al. 2013

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Sarcoidosis is a systemic granulomatous disease of unknown origin. We herein report a case of sarcoidosis in a chronic dialysis patient diagnosed by hypercalcemia without any common clinical manifestations. The onset of sarcoidosis in chronic dialysis patients is rare; to the best of our knowledge, only 23 cases have been reported. Evaluation of the 23 previously published cases revealed that a diagnosis of sarcoidosis was often achieved by the presence of sarcoidosis-related hypercalcemia without any common clinical presentations, as in the present case. This characteristic may arise from a specific immune deficiency and the unique physiology of 1,25-dihydroxyvitamin D3, a main cause of sarcoidosis-related hypercalcemia, in chronic dialysis patients. These clinical features may be useful to understand the pathogenesis of sarcoidosis.

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