A Case of Surgical Treatment of Solitary Splenic Metastasis After a Curative Resection of Early Gastric Cancer

Shirai, Satoru; Igarashi, Tatsunori; Watanabe, Kazuyoshi; Kohno, Fumitaka; Hayashi, Tomoyuki; Yoshida, Katsutoshi; Hanyu, Fujio; Kobayashi, Seiichiro

doi:10.3919/ringe1963.53.3012

Cited by 3 publications

(5 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, there have been 19 reported cases of radical treatment by splenectomy for isolated splenic metastasis from gastric cancer, which comprised 5 cases of synchronous metastasis and 14 cases of metachronous metastasis (including our case) (Table 1) [4, 5, 9–23]. In our analysis of these cases, categorization by sex revealed a male predominance (16 men and 3 women).…”

Section: Discussionmentioning

confidence: 71%

“…For the present report, searches were performed for related reports published between April 1983 and October 2016 in Japan Medical Abstracts Society Web (the largest medical database in Japanese), and from the earliest possible date to October 2016 in PubMed, using the keywords “splenic metastasis,” “gastric cancer,” and “gastric neoplasms”. To our knowledge, there have been 19 reported cases of radical treatment by splenectomy for isolated splenic metastasis from gastric cancer, which comprised 5 cases of synchronous metastasis and 14 cases of metachronous metastasis (including our case) (Table 1 ) [ 4 , 5 , 9 – 23 ]. In our analysis of these cases, categorization by sex revealed a male predominance (16 men and 3 women).…”

Section: Discussionmentioning

confidence: 99%

“…The prognosis of an isolated splenic metastasis from gastric cancer treated by splenectomy is unclear because of its rarity. All past reports [ 4 , 5 , 9 – 23 ] have been case reports only, and the postsurgical follow-up periods were comparatively short. One study reported that it is possible for some patients with synchronous splenic metastasis to obtain long-term survival, whereas patients with metachronous metastasis have a poor prognosis [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

“…Once splenic metastasis from gastric cancer occurs, it is usually accompanied by multiorgan metastasis and dissemination [ 1 – 3 ]. Only a few case reports have documented isolated splenic metastasis from early gastric cancer [ 4 , 5 ]. In this paper, we present a very rare case of a solitary splenic metastasis from early gastric cancer.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Curative resection by splenectomy for solitary splenic metastasis from early gastric cancer: a case report and literature review

et al. 2017

View full text Add to dashboard Cite

BackgroundSolitary metastasis of a malignancy to the spleen is rare, particularly for gastric cancer. Only a few case reports have documented isolated splenic metastasis from early gastric cancer. We describe a case of splenic metastasis from early gastric cancer.Case presentationA 60-year-old man underwent a distal gastrectomy for early gastric cancer. It infiltrated the submucosa with pathological nodal involvement (pT1bN2M0, stage IIB). One year after the gastrectomy, an abdominal computed tomography scan showed a low-density lesion, 17 mm in diameter, at the upper pole of the spleen. Positron emission tomography/computed tomography showed focal accumulation of fluorine-18 fluorodeoxyglucose in the spleen without extrasplenic tumor dissemination or metastasis. We diagnosed splenic metastasis of gastric cancer, and performed a splenectomy. Histological examination confirmed moderately differentiated tubular adenocarcinoma and poorly differentiated adenocarcinoma (solid type) that was consistent with the features of the primary gastric cancer. The splenic tumor was pathologically and immunohistochemically diagnosed as a metastasis from the gastric carcinoma. More than 18 months after the splenectomy, the patient has had no evidence of recurrent gastric cancer.ConclusionWhen solitary metastasis to the spleen is suspected during the postoperative follow-up of a patient with gastric cancer, a splenectomy is a potentially effective treatment.

show abstract

Section: Discussionmentioning

confidence: 71%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Curative resection by splenectomy for solitary splenic metastasis from early gastric cancer: a case report and literature review

et al. 2017

View full text Add to dashboard Cite

show abstract

“…2 In an autopsy series of 7 165 cases of carcinoma, 312 and 22 cases of splenic metastasis were found among 4 404 cases of metastases (7.1%) and 533 cases of gastric cancer (4.1%), respectively. 2,[5][6][7][8][9][10][11][12][13] The primary tumors were located in the upper to middle third of the stomach, except in two cases. 4 Table 1 summarizes six cases of synchronous splenic metastasis and five cases of metachronous splenic metastasis from gastric cancer, including the present case.…”

Section: Discussionmentioning

confidence: 99%

Solitary Splenic Metastasis from Gastric Cancer: Report of a Case

et al. 2002

View full text Add to dashboard Cite

We report a rare case of metachronous and solitary metastasis to the spleen from gastric cancer. A 69-year-old man who had undergone a distal gastrectomy for gastric cancer 48 months earlier was found to have a solitary lesion in the spleen, and an increased serum carcinoembryonic antigen (CEA) level. The patient underwent a laparotomy for suspected metastasis to the spleen. At laparotomy, a tumor was found in the upper pole of the spleen without involvement of other organs, and a splenectomy was performed. Histological examination confirmed that the splenic tumor was a well-differentiated adenocarcinoma similar to the primary gastric cancer. The postoperative course was uneventful and his serum CEA decreased to within normal levels. The patient died of multiple metastases to the liver and peritoneal dissemination 40 months after the splenectomy.

show abstract