A case of Sweet's syndrome following septic pulmonary emboli after high‐dose chemotherapy for advanced testicular cancer

Abstract

A 33-year-old man with advanced testicular cancer underwent high-dose chemotherapy combined with peripheral blood stem cell transplantation. After administration of granulocyte colony-stimulating factor (G-CSF), multiple infiltrative erythema was identified on the face, thigh, and lower leg. A dermatologist diagnosed this as Sweet's syndrome caused by G-CSF; consequently G-CSF administration was stopped. When the skin lesions had improved, phlebitis was found at the injection site of the peripheral vein catheter. The patient then suffered from sudden left chest pain and dyspnea. Chest computed tomography showed the characteristic findings of septic pulmonary emboli (SPE). He was treated by the administration of vancomycin, fluconazole, and pazufloxacin mesilate. Although Sweet's syndrome and SPE are rare diseases, the presence of these diseases must be considered when performing chemotherapy for urological malignancy.

High dose chemotherapy including paclitaxel (T‐ICE) combined with peripheral blood stem cell transplantation for male germ cell tumor. Preliminary report

“…Although we experienced the rare side‐effects Sweet's syndrome and septic pulmonary emboli, these diseases were successfully managed by steroids and antibiotics, respectively. The details of that particular case are reported elsewhere 3 . No life threatening toxicities were detected.…”

“…He was recovered by administration of antibiotics. Since these two complications are rare, we report this case as a case report 3 …”