A case of symptomatic Rathke's cyst

Abstract

Rathke's cleft cyst is a benign growth found on the pituitary gland in the brain, specifically a fluid-filled cyst in the posterior portion of the anterior pituitary gland. It occurs when the Rathke's pouch does not develop properly, and ranges in size from 2 to 40 mm in diameter. Asymptomatic cysts are common, detected during autopsies of 2–26% of individuals who have died of unrelated causes. Symptomatic cysts are rare and only approximately 150 cases have been reported. Females are twice as likely as males to have a cyst. Symptomatic cysts can trigger visual disturbances, pituitary dysfunction and headaches. Here we present a case of a 40-year-old female patient who presented with complains of visual disturbances, headache and amenorrhoea. On investigations, MRI of brain revealed findings suggestive of Rathke's cleft cyst.

Atypical sellar cyst: A rare case

“…Previously many cases of symptomatic sellar Rathke's cleft cysts [8,10] and intrasellar arachnoid cysts [4,9] have been reported but our case is unique, as no previous case of a sellar cyst with histological findings similar to ours has so far been reported (to the best of our knowledge).…”

Rathke's Cleft Cyst or Pituitary Apoplexy: A Case Report and Literature Review

“…In the second group, an increase in the signal on T1WI has been related to the high content of mucopolysaccharides, which is believed to result from an increase in the number of mucin-secreting cells in the cyst wall, as well as from an increase in the activity of these cells. Rathke cleft cysts do not enhance after contrast material administration, although an enhancing rim of the displaced compressed pituitary gland is present in approximately half of the cases [ 16 ].…”

Change of central and peripheral vision in patient with symptomatic cyst of Rathke's cleft following transsphenoidal resection

“…U žien sa vyskytujú dvakrát častejšie ako u mužov. Symptoma-tické cysty sa prejavujú cefaleou, poruchami videnia, prípadne endokrinologickými symptómami [11]. V niektorých prípadoch boli u pacientov s cystou Rathkeho púzdra zaznamenané zvýšené hladiny sérového prolaktínu.…”

“…Typickým znakom v zobrazovacých vyšetreniach je nekalcifikovaná intraselárna a/alebo supraselárna cysta s intracystickým uzlom. Podľa magnetickej rezonancie ich najčastejšie rozdeľujeme na cystu Rathkeho púzdra s nízkou intenzitou signálu pri T1 vážení a vysokou intenzitou signálu pri T2 vážení alebo s vysokou intenzitou signálu pri T1 vážení a premenlivou intenzitou signálu pri T2 vážení [11].…”