A case of tuberculosis verrucosa cutis in Brazil undiagnosed for 15 years

Wedy, Glaucia Ferreira; Passero, Luiz Felipe Domingues; Criado, Paulo Ricardo; Belda, Walter

doi:10.1016/j.bjid.2021.101593

Cited by 3 publications

(3 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most frequent predilections are lower extremities, buttocks, and trunks. 17 So, the predilection of this case on the face is quite rare because we often find cutaneous tuberculosis in the trunk or extremities. The principle of cutaneous tuberculosis's treatment as extrapulmonary tuberculosis is the same as pulmonary tuberculosis and should be paid attention to.…”

Section: Case Reportmentioning

confidence: 83%

Successful Treatment of Relapse Cutaneous Tuberculosis on Pregnant Woman with Ethambutol Allergic

Widjaja,

Puspitasari,

Nathania

2023

J. Med. Health

View full text Add to dashboard Cite

Tuberculosis infection among pregnant women often reveals unspecific clinical manifestations, and cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis. The aim of this case report is to manage well Extra-Pulmonary tuberculosis manifestation, especially in pregnant women. A Pregnant woman with a gestational age of 6-7 weeks complained of red spots on cheeks. One year ago, the patient suffered cutaneous tuberculosis and was only treated with Rifampicin, Isoniazid, and Levofloxacin; pyrazinamide and ethambutol were not given due to a strong suspicion of allergy. Physical examination revealed plaque with scales, and PCR examination revealed Mycobacterium tuberculosis. She suffered relapse of cutaneous tuberculosis and was given rifampicin, isoniazid, and pyrazinamide. After 2 weeks the skin lesion improved significantly, and ethambutol was added to the regimen. The patient suffered from drug eruption, ethambutol was discontinued, and the skin lesion disappeared after four months of treatment. The regiment was continued for one year; showed better condition and delivered a healthy baby boy. Cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis (1-1.5%) and is hard to diagnose and treat, especially in pregnant women. Allergic to one of its drugs can increase its risk of being resistant and increase its mortality and morbidity. As conclusion, prompt treatment is needed for tuberculosis patients, especially pregnant women. Early detection and examinations are required to diagnose it properly.

show abstract

Section: Case Reportmentioning

confidence: 83%

Successful Treatment of Relapse Cutaneous Tuberculosis on Pregnant Woman with Ethambutol Allergic

Widjaja,

Puspitasari,

Nathania

2023

J. Med. Health

View full text Add to dashboard Cite

show abstract

“…17 This disease often occurs in health workers, laboratory workers, farmers, butchers, and infected children through contact with contaminated soil. 10 TBC commonly infects the lungs, so in patients with tuberculosis verrucosa cutis, a chest x-ray is required to look for focal infection. 7,15 In this patient, the chest X-ray showed pulmonary TBC and Diabetes Mellitus (DM), shown by the result of HbA1c and FBG tests.…”

Section: Discussionmentioning

confidence: 99%

“…8 Tuberculosis verrucosa cutis is classified as a form of cutaneous tuberculosis, a paucibacillary disease caused by exogenous reinfection (inoculation) after sensitization on the immunocompromised individual. 7,9,10,11 In Europe, the lesions are commonly found on the arms, while in Asia, the lesions are in the ankles and glutes. The lesions are initially present as a wart-like papule that is progressively expanding.…”

Section: Introductionmentioning

confidence: 99%

Tuberculosis verrucosa cutis in a patient with pulmonary tuberculosis: A case report

Maulida,

Earlia,

Vella

et al. 2023

JKKI

View full text Add to dashboard Cite

Cutaneous tuberculosis is a skin disorder caused by Mycobacterium tuberculosis, commonly classified according to its spreading route into endogenous, exogenous, and hematogenous, with distinct skin morphology and histopathological findings. Tuberculosis verrucosa cutis is a classification form of cutaneous tuberculosis, a paucibacillary disease caused by exogenous reinfection (inoculation) after sensitization on an immunocompromised individual. Management of cutaneous TB is generally similar to the management of pulmonary TB. In this paper, we presented a case of 62 years old male with a purplish rough patch on the right dorsum of the foot that began 1,5 years. There is a history of trauma and pulmonary TB. On the right dorsum of the foot, we identified a verrucous lesion with a livid base, irregular with the size of 6x3 cm. The diagnosis is established based on clinical features and histopathology evaluation. The patient received treatment with antituberculosis medication, topical mupirocin ointment 2%, and vaseline petroleum jelly. Improvement of the lesions was observed after the patient completed the intensive phase in two months of treatment with antituberculosis drugs.

show abstract

Tuberculosis Verrucous Cutis Mimicking Chromoblastomycosis

Septiafni

Pamudji

Rusmawardiana

et al. 2022

The International Journal of Mycobacteriology

View full text Add to dashboard Cite

Tuberculosis verrucous cutis (TBVc) is a skin infection caused by M. tuberculosis, characterized by the presence of a solitaire verrucous plaque but may present as a varies of different clinical morphologies on the finger and or feet. The diagnosis is often late because of its mimicking other diseases with different etiology. Bacterial culture examination is negative because there are few pathogens in the lesion. Meanwhile, other diagnostic methods provide lower sensitivity and specificity which add further diagnostic challenges. We presented one case report of TBVc mimicking chromoblastomycosis. A 26-year-old man complain a multiple papule-plaque verrucose on the dorsum of the right foot and extending to all of fingers for 2 years ago. The first lesion appears as a small papule verrucous then progressively to form plaque with curst yellow-red and central healing. Examination of bacterial culture with Ziehl–Neelsen stain and GeneXpert did not find M. tuberculosis but could not rule out the diagnosis of TBVc. The diagnosis was established based on the correlation of clinical manifestations and dermoscopy with histopathological examination. To date, there is no gold standard for TBVc testing. Correlation analysis of clinical manifestations, dermoscopy, and histopathology can be considered to establish the diagnosis of TBVc, especially if the culture is negative and the limitations of polymerase chain reaction tools.

show abstract

A case of tuberculosis verrucosa cutis in Brazil undiagnosed for 15 years

Cited by 3 publications

References 14 publications

Successful Treatment of Relapse Cutaneous Tuberculosis on Pregnant Woman with Ethambutol Allergic

Successful Treatment of Relapse Cutaneous Tuberculosis on Pregnant Woman with Ethambutol Allergic

Tuberculosis verrucosa cutis in a patient with pulmonary tuberculosis: A case report

Tuberculosis Verrucous Cutis Mimicking Chromoblastomycosis

Contact Info

Product

Resources

About