A Case of Tuberculous Sinusitis Without Concomitant Pulmonary Disease

Beltran, S.; Douadi, Y.; Lescure, F.-X.; Hanau, M.; Laurans, G.; Ducroix, J.P.

doi:10.1007/s10096-002-0850-x

Cited by 13 publications

(4 citation statements)

References 5 publications

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“…Furthermore, as we have encountered in our patient, it might often mimic, from the clinicoradiologic perspective, fungal rhinosinusitis, sinonasal neoplasms (including inverted papilloma, natural killer T cell lymphoma), other granulomatous diseases (such as Wegner's granulomatosis, syphilis, leprosy, sarcoidosis, rhinoscleroma, rhinitis sicca), and retained foreign bodies(8). Beltran et al(11) proposed that the diagnosis of sinonasal tuberculosis should be based on the following criteria: a) absence of clinical response to empirical antibiotics, b) presence of caseous granulomatous inflammatory lesions in the histopathological analysis, and c) identification of Mycobacterium tuberculosis in the surgical specimen. It is true that patients with sinonasal tuberculosis often present with considerable clinical variations.…”

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confidence: 70%

Primary Sinonasal Tuberculosis: A Diagnostic Challenge

Dey

Misra

Dutta

2018

Turk Arch Otorhinolaryngol

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Primary sinonasal tuberculosis remains a diagnostic challenge as it mimics sinonasal granulomatous disease or neoplasms. Its characteristic signs and symptoms may be non-specific and highly variable. Here we report a unique clinical condition of a 24-year-old man who presented with unilateral nasal obstruction and epiphora for 2 years. He was without any comorbidity, was immunocompetent, and was otherwise healthy. Subsequent investigations, including a computed tomography scan of the paranasal sinuses, and perioperative findings revealed a sinonasal mass involving the lateral nasal wall and paranasal sinuses. The histopathology was consistent with the features of tuberculosis. There was no evidence of pulmonary or any other primary tubercular foci elsewhere in the body, suggesting the diagnosis of primary sinonasal tuberculosis.

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confidence: 70%

Primary Sinonasal Tuberculosis: A Diagnostic Challenge

Dey

Misra

Dutta

2018

Turk Arch Otorhinolaryngol

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“…proposed that the diagnosis of sinonasal TB should be based on the following criteria: The absence of a clinical response to empirical antibiotics, the presence of caseous granulomatous inflammatory lesions on histopathology, and identification of Mycobacterium TB in the surgical specimen. [ 14 ] The main diagnostic problem is that nasal TB mimics other granulomatous diseases of nose and malignancy. On histology, both caseating and noncaseating granulomas have been described.…”

Section: Discussionmentioning

confidence: 99%

Primary Nasal Tuberculosis: Resurgence or Coincidence − A Report of Four Cases with Review of Literature

2017

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Background:Primary nasal tuberculosis (TB) is a rare form of TB even in areas with high TB incidence. It is timely diagnosis and proper management are often delayed due to its rarity and nonspecific clinical presentation.Aim:The aim of the study was to review histopathologically diagnosed cases of nasal TB over a period of 1 year and to describe its clinical presentation, diagnostic workup, the importance of histopathological diagnosis along with a brief review of the literature.Materials and Methods:This was a retrospective study done in the Department of Pathology of a Tertiary Care Hospital of Delhi over a period of 1 year where all the cases with histopathological diagnosis of nasal TB were reviewed. Patients' clinical details, investigations and treatment details along with follow-up were obtained from the medical records section. For each case, routine hematoxylin and eosin stain were studied along with Ziehl–Neelson staining.Results:A total of four patients were diagnosed with nasal TB histopathologically. Patients' age ranged from 5 to 34 with an equal male to female ratio. All patients were immunocompetent. Primary nasal TB was seen in all of the four cases. None of the cases, it was clinically suspected, and histopathology was the mainstay of diagnosis. All the cases were treated with antituberculous treatment and showed considerable improvement.Conclusions:Although nasal TB is rare, it should be considered in the differential diagnosis of chronic nasal symptoms and granulomatous lesions of the nose. Histopathology plays an important role in the diagnosis of these clinically unsuspecting cases of nasal TB.

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“…However, often, neither the pathological nor bacteriological confirmation of TB is possible and hence, the diagnosis is made only on the basis of the patient's response to the ATT. 12 Nevertheless, this rare clinical entity carries an excellent prognosis when treated correctly with ATT consisting of isoniazid, rifampicin, ethambutol and pyrazinamide for at least a period of 6 months as complete resolution of the disease is seen.…”

Section: Discussionmentioning

confidence: 99%